Basal Cell Tumor in a Japanese Macaque (Macaca fuscata)
Basal Cell Tumor in a Japanese Macaque (Macaca fuscata)
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日本猕猴（Macaca fuscata）的基底细胞肿瘤
DOI：
10.1177/030098589503200316
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发表时间：
1995
期刊：
影响因子：
--
通讯作者：
K. Ueda
中科院分区：
文献类型：
--
作者：
T. Yanai;S. Wakabayashi;T. Masegi;T. Iwasaki;K. Yamazoe;K. Ishikawa;K. Ueda
对野生捕获的雌性日本猕猴（Macaca fuscata）一例罕见的皮肤基底细胞瘤进行了研究。肿瘤生长在真皮和皮下，由类似基底细胞的细胞组成，表现为带状、实性、腺性和囊性混合模式。肿瘤被纤维结缔组织的压缩区与周围的正常组织分开。细胞核圆形，深染，具有单个位于中央的核仁。有丝分裂象很常见。免疫组化结果显示上皮膜抗原、角蛋白和细胞角蛋白AE3阳性。电镜检查显示细胞质中有少量张力丝。
A rare case of basal cell tumor of the skin in a wild-caught female Japanese macaque (Macaca fuscata) was studied. Tumor growth, which was composed of cells resembling basal cells, was observed in the dermis and subcutis and showed a mixture of ribbon, solid, glandular, and cystic patterns. The tumor was separated from surrounding normal tissue by a compressed zone of fibrous connective tissue. The nuclei were round and hyperchromatic and possessed a single centrally located nucleolus. Mitotic figures were common. Immunohistochemically, a positive reaction for epithelial membrane antigen, keratin, and cytokeratin AE3 was evident. Electron microscopic examination revealed a small number of tonofilaments in the cytoplasm.