Differential screening technology in the service of ovarian biology.
Differential screening technology in the service of ovarian biology.
复制标题
差异筛选技术服务于卵巢生物学。
DOI：
10.1023/a:1012792500403
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发表时间：
2002
影响因子：
8.2
通讯作者：
Adashi,EliY
中科院分区：
文献类型：
--
作者：
Tavares,AdrianoB;Adashi,EliY
基因表达变化的鉴定一直是现代生物医学研究的目标。为了更好地理解控制细胞内稳态的生理事件，有必要认识到哪些基因参与了这些事件以及它们是如何被调节的。结论基因组测序的一些物种提供了一个独特的机会来破译分子控制在细胞水平。特定组织中单个基因或一组基因表达模式的修饰可能提供功能线索，因为类似的基因表达模式可能与类似的功能相关。因此，比较基因组学可能被视为理解生物现象的有用工具。
The identification of changes in gene expression has been a goal of modern biomedical research. In an attempt to better understand the physiologic events that control cellular homeostasis, it is essential that one be able to recognize which genes are involved in such events and how they are regulated. The conclusion of the sequencing of the genome of a number of species provides a unique opportunity to decipher molecular control at the cellular level.Modifications of the pattern of expression of a single gene or a set of genes within a specific tissue may provide functional clues in that comparable patterns of gene expression are likely to be associated with similar functions. Therefore, comparative genomics may be viewed as a helpful tool for the understanding of biological phenomena.