Lipid-derivatized poly(ethylene glycol) micellar formulations of benzoporphyrin derivatives
Lipid-derivatized poly(ethylene glycol) micellar formulations of benzoporphyrin derivatives
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DOI：
10.1016/s0168-3659(02)00442-x
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发表时间：
2003-01-17
影响因子：
10.8
通讯作者：
Boch, R
中科院分区：
文献类型：
--
作者：
Zhang, JX;Hansen, CB;Boch, R
In this paper, we describe the development of micellar formulations for increasing the solubility of lipophilic benzoporphyrins. Using a simple procedure that is readily adaptable for large-scale manufacturing, both A-ring (1) and B-ring isomers (2) of benzoporphyrins could be readily formulated, at concentrations up to 1-2 mg/ml, into small micelles (
