3H‐Estradiol, 3H‐Testosterone and 3H‐Dihydrotestosterone localization in the brain of the lizard Anolis carolinensis: An autoradiographic study
3H‐Estradiol, 3H‐Testosterone and 3H‐Dihydrotestosterone localization in the brain of the lizard Anolis carolinensis: An autoradiographic study
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3H-雌二醇、3H-睾酮和 3H-二氢睾酮在蜥蜴 Anolis carolinensis 大脑中的定位：放射自显影研究
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发表时间：
1979
期刊：
影响因子：
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通讯作者：
D. Pfaff
中科院分区：
文献类型：
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作者：
J. Morrell;D. Crews;A. Ballin;A. Morgentaler;D. Pfaff
这些实验已经证明了美国变色龙Anolis carolinensis脑中性激素集中细胞的存在和神经解剖学拓扑结构。给予3 H-雌二醇后，在杏仁核、隔、内侧视前区、下丘脑前区、下丘脑腹内侧核和室周核和垂体前叶中发现大量激素浓缩细胞。此外，标记细胞被发现在隆凸，峡部小细胞核内和周围。在腭吻侧、第五脑神经运动核、中缝核和脊髓中也有少量标记细胞。给予3 H-睾酮或3 H-双氢睾酮后，神经解剖学模式与给予3 H-雌二醇后发现的非常相似;然而，给予雄激素后观察到的标记细胞较少。两个例外的模式相似的尾侧部分的腭和中脑被盖区。在给予3 H-睾酮或3 H-双氢睾酮后发现激素浓缩细胞，而在给予3 H-雌二醇后，这两个区域的标记细胞非常罕见。对于每种激素，雄性和雌性大脑中激素集中细胞的模式是相同的。爬行动物的视前区、下丘脑和垂体前叶已被证明参与神经内分泌调节和性行为的控制。
The presence and the neuroanatomical topography of sex hormone concentrating cells in the brain of the American chameleon, Anolis carolinensis have been demonstrated by these experiments. After 3H‐estradiol administration large numbers of hormone concentrating cells were found in the amygdala, septum, medical preoptic area, anterior hypothalamic area, the ventromedial and periventricular nuclei of the hypothalamus, and anterior pituitary. In addition, labelled cells were found in the torus semicircularis, in and around the nucleus isthmus pars parvocellularis. A small number of labelled cells could also be found in the rostral pallium, motor nucleus of the fifth cranial nerve, the raphe nuclei, and the spinal cord. After 3H‐testosterone or 3H‐dihydrotestosterone administration the neuroanatomical pattern was very similar to that found after 3H‐estradiol; however, fewer labelled cells were seen after the androgens were given. Two exceptions to the similarity of pattern were in a caudal part of the pallium and in the mesencephalic tegmental area. Hormone‐concentrating cells were found after 3H‐testosterone or 3H‐dihydrotestosterone administration, while labelled cells in these two areas after 3H‐estradiol administration were extremely rare. The pattern of hormone‐concentrating cells was the same in male and female brains, for each of the hormones. The preoptic area, hypothalamus, and anterior pituitary have been demonstrated in reptiles to be involved in neuroendocrine regulation and in the control of sex behaviors.