Complete genomic DNA sequence of rock bream iridovirus

Complete genomic DNA sequence of rock bream iridovirus
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DOI:
10.1016/j.virol.2004.05.008
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发表时间:
2004-08-01
期刊:
影响因子:
3.7
通讯作者:
Park, JW
Park, JW
中科院分区:
医学3区
文献类型:
--
作者:
Do, JW;Moon, CH;Park, JW

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虹彩病毒是在韩国养殖的条石鲷(Oplegnathus fasciatus)中引起动物流行病的病原体。在这里,我们报告的完整基因组序列的岩鲷虹彩病毒(RBIV)。RBIV基因组全长112080 bp,含有至少118个开放阅读框(ORF),基因组结构与传染性脾肾坏死病毒(ISKNV)相似。通过对RBIV的主要衣壳蛋白(MCP)、DNA修复蛋白RAD2和DNA聚合酶B家族的系统发育分析,发现RBIV与红鲷虹彩病毒(RSIV)、石斑鱼昏睡病虹彩病毒(GSDIV)、矮鲈虹彩病毒(DGIV)和ISKNV的亲缘关系最近。该基因组序列提供了有关虹彩病毒在养殖鱼类中的进化和分化的有用信息。(C)2004年爱思唯尔公司所有的紧身衣保留。
Iridovirus is a causative agent of epizootics among cultured rock bream (Oplegnathus fasciatus) in Korea. Here, we report the complete genomic sequence of rock bream iridovirus (RBIV). The genome of RBIV was 112080 bp long and contained at least 118 putative open reading frames (ORFs), and its genome organization was similar to that of infectious spleen and kidney necrosis virus (ISKNV). Of the RBIV's 118 ORFs, 85 ORFs showed 60-99% amino acid identity to those of ISKNV Phylogenetic analysis of major capsid protein (MCP), DNA repair protein RAD2, and DNA polyinerase type-B family indicated that RBIV is closely related to red sea bream iridovirus (RSIV), Grouper sleepy disease iridovirus (GSDIV), Dwarf gourami iridovirus (DGIV), and ISKNV. The genome sequence provides useful information concerning the evolution and divergence of iridoviruses in cultured fish. (C) 2004 Elsevier Inc. All tights reserved.