1995 SMR young investigators' award finalist: MR measurement of time‐dependent blood pressure variations

1995 SMR young investigators' award finalist: MR measurement of time‐dependent blood pressure variations
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1995 年 SMR 青年研究者奖决赛入围者:时间依赖性血压变化的 MR 测量

DOI:
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发表时间:
1995
影响因子:
4.4
通讯作者:
D. Plewes
D. Plewes
中科院分区:
医学2区
文献类型:
--
作者:
S. Urchuk;D. Plewes

文献摘要

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介绍了一种测量血管内压力变化的磁共振成像方法。该技术是基于血管顺应性和血管扩张的估计,这是通过空间和时间的速度导数的相关性和流动方向的速度梯度的测量得到的。该技术的准确性是通过在体外进行脉动流的可膨胀血管模型中获得的MR和传感器压力测量值的比较来确定的。结果表明,在覆盖生理顺应范围的幻影中,均方根误差可达4-12%。在体内的可行性是通过胸主动脉压力测量来证明的,它产生的压力波形具有预期的形状和大小。
An MR imaging method for measuring intravascular pressure variations is introduced. The technique is based on estimates of vascular compliance and vessel distension, which are obtained from a correlation of spatial and temporal velocity derivatives and measurements of the velocity gradient in the direction of flow, respectively. The accuracy of the technique was determined in vitro through a comparison of MR and transducer pressure measurements obtained in distensible vessel phantoms undergoing pulsatile flow. Results indicated that a root‐mean‐square error of 4–12% can be expected in phantoms covering a physiological range of compliance. In vivo feasibility was demonstrated by thoracic aorta pressure measurements, which produced pressure waveforms with an expected shape and magnitude.