In vivo trapping of polyketide intermediates from an assembly line synthase using malonyl carba(dethia)-N-acetyl cysteamines.
In vivo trapping of polyketide intermediates from an assembly line synthase using malonyl carba(dethia)-N-acetyl cysteamines.
复制标题
使用丙二酰卡巴（脱硫）-N-乙酰半胱胺在体内捕获来自装配线合酶的聚酮化合物中间体。
作者：
M. Tosin;Yuliya Demydchuk;James S. Parascandolo;C. Per;F. Leeper;P. Leadlay
Early-stage intermediates in the biosynthesis of erythromycin A by Saccharopolyspora erythraea were intercepted by malonyl carba(dethia)-N-acetyl cysteamines, generated in vivo from the hydrolysis of the corresponding methyl esters.
影响因子：
15
作者：
Valenzano, Chiara R.;Lawson, Rachel J.;Chen, Alice Y.;Khosla, Chaitan;Cane, David E.
通讯作者：
Cane, David E.
影响因子：
14.8
作者：
Sun Y;Hahn F;Demydchuk Y;Chettle J;Tosin M;Osada H;Leadlay PF
通讯作者：
Leadlay PF
影响因子：
16.6
作者：
Moldenhauer, Jana;Goetz, Daniel C. G.;Piel, Joern
通讯作者：
Piel, Joern