Chronic Intra Oral Pain and Depressive Symptoms in Japanese Community-Dwelling Elderly: A Longitudinal Study
Chronic Intra Oral Pain and Depressive Symptoms in Japanese Community-Dwelling Elderly: A Longitudinal Study
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DOI：
10.1922/cdh_4200hanindriyo07
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发表时间：
2018-06-01
影响因子：
1.7
通讯作者：
Miyazaki, Hideo
中科院分区：
文献类型：
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作者：
Hanindriyo, Lisdrianto;Yoshihara, Akihiro;Miyazaki, Hideo
目的：老年人重度抑郁症发病率为0.2 ~ 14.1/100人年，临床相关抑郁症状发生率为6.8/100人年。本研究旨在评估日本老年人慢性口腔内疼痛与抑郁症状之间的纵向关系。基础研究设计：3年队列研究。研究对象：2005年居住在日本新泻市的212名77岁社区老人（男性129人，女性83人）。干预措施：在基线时，受试者被问及慢性口腔内疼痛（牙齿、牙龈或假牙疼痛），回答选择“是”或“否”。任何类型的疼痛均被视为慢性口腔内疼痛。主要观察指标：随访时采用一般健康问卷30 （GHQ-30）评估抑郁程度。使用东京都老年学研究所（TMIG）能力指数评估日常生活活动。结果：在多因素logistic回归中，在调整血清HbA1c、肌酐和工作年限后，基线口内疼痛预测随访时的抑郁症状（优势比= 3.2,95% CI = 1.32-7.81）。结论：慢性口腔内疼痛增加了老年人出现抑郁症状的风险。
Objective: The incidence of major depressive disorder in the elderly ranges from 0.2 to 14.1/100 person-years, and the incidence of clinically relevant depressive symptoms is 6.8/100 person-years. This study aimed to assess the longitudinal relationship between chronic intra oral pain and depressive symptom in Japanese elderly. Basic research design: 3-year cohort study. Participants: 212 community-dwelling seniors (129 men, 83 women) aged 77 years residing in the city of Niigata, Japan in 2005. Interventions: At baseline, subjects were asked about chronic intra oral pain (tooth, gingival or denture pain), with response choices of "yes" or "no". Any type of pain, was counted as chronic intra oral pain. Main outcome measures: The General Health Questionnaire 30 (GHQ-30) was used to assess depression at follow up. The Tokyo Metropolitan Institute of Gerontology (TMIG) Index of Competence was used to assess activities of daily living. Results: In multivariate logistic regression, baseline intra oral pain predicted depressive symptoms at follow up (Odds Ratio = 3.2, 95% CI = 1.32-7.81) after adjusting for serum HbA1c, creatinine and working life. Conclusions: Chronic intra oral pain increased the risk for the development of depressive symptoms in the elderly.