Microfluidic devices powered by integrated elasto-magnetic pumps.
Microfluidic devices powered by integrated elasto-magnetic pumps.
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DOI：
10.1039/d0lc00935k
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发表时间：
2020-11-10
期刊：
影响因子：
6.1
通讯作者：
Ogrin FY
中科院分区：
文献类型：
--
作者：
Binsley JL;Martin EL;Myers TO;Pagliara S;Ogrin FY
集成弹性磁力泵为便携式微流体设备提供动力，用于现场检测。我们展示了非对称弹磁系统如何为芯片实验室和床旁设备提供新型集成泵送解决方案。这种整体泵送解决方案的灵感来自于珀塞尔的3连杆游泳器，它集成在一个简单的微流体设备中，绕过了外部连接的要求。我们实验证明，该系统可以提供可调的流体流量高达600 μL h-1。这种流体流动通过使用弱的、均匀的、单轴的振荡磁场致动泵来实现，磁场振幅在3-6 mT的范围内。重要的是，可以通过调节驱动频率来逆转流体流动。我们的实验证明，该设备可以成功地操作的粘度范围内的流体，在较高的粘度泵送相关的最佳驱动频率降低。这里通过检查弹磁部件的非往复运动来理解由该装置产生的流体流动。该器件能够用一个简单、集成的芯片实验室组件取代外部泵送系统。
Integrated elasto-magnetic pumps power portable microfluidic devices for point of care testing. We show how an asymmetric elasto-magnetic system provides a novel integrated pumping solution for lab-on-a-chip and point of care devices. This monolithic pumping solution, inspired by Purcell's 3-link swimmer, is integrated within a simple microfluidic device, bypassing the requirement of external connections. We experimentally prove that this system can provide tuneable fluid flow with a flow rate of up to 600 μL h–1. This fluid flow is achieved by actuating the pump using a weak, uniform, uniaxial, oscillating magnetic field, with field amplitudes in the range of 3–6 mT. Crucially, the fluid flow can be reversed by adjusting the driving frequency. We experimentally prove that this device can successfully operate on fluids with a range of viscosities, where pumping at higher viscosity correlates with a decreasing optimal driving frequency. The fluid flow produced by this device is understood here by examining the non-reciprocal motion of the elasto-magnetic component. This device has the capability to replace external pumping systems with a simple, integrated, lab-on-a-chip component.
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影响因子：
4.6
作者：
Hamilton JK;Petrov PG;Winlove CP;Gilbert AD;Bryan MT;Ogrin FY
通讯作者：
Ogrin FY
影响因子：
1.4
作者：
Gadelha, Hermes
通讯作者：
Gadelha, Hermes
影响因子：
7.8
作者：
Gutman, Emiliya;Or, Yizhar
通讯作者：
Or, Yizhar
影响因子：
6.1
作者：
Fahrni, Francis;Prins, Menno W. J.;van IJzendoorn, Leo J.
通讯作者：
van IJzendoorn, Leo J.
影响因子：
--
作者：
GHEBER, L;PRIEL, Z
通讯作者：
PRIEL, Z