Single-cell genomics

Single-cell genomics
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DOI:
10.1038/nmeth0411-311
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发表时间:
2011-04-01
期刊:
影响因子:
48
通讯作者:
Quake, Stephen R.
Quake, Stephen R.
中科院分区:
生物学1区
文献类型:
--
作者:
Kalisky, Tomer;Quake, Stephen R.

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单细胞分辨率的基因组分析方法使人们能够对复杂的生物现象有新的理解。单细胞技术,从流式细胞术和微流体到PCR和测序,用于了解复杂组织的细胞组成,发现新的微生物物种并进行全基因组单体型分析。
Methods for genomic analysis at single-cell resolution enable new understanding of complex biological phenomena. Single-cell techniques, ranging from flow cytometry and microfluidics to PCR and sequencing, are used to understand the cellular composition of complex tissues, find new microbial species and perform genome-wide haplotyping.