Incidence and risk factors of low birth weight babies born in Dhulikhel Hospital

Incidence and risk factors of low birth weight babies born in Dhulikhel Hospital
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Dhulikhel 医院出生的低出生体重儿的发生率及危险因素

DOI:
10.3126/jiom.v32i3.4959
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发表时间:
1970
期刊:
影响因子:
--
通讯作者:
S. Marahatta
S. Marahatta
中科院分区:
--
文献类型:
--
作者:
Sd Singh;S. Shrestha;S. Marahatta

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世界卫生组织将低出生体重定义为出生体重低于2500克。东南亚地区近三分之一的新生儿是低出生体重婴儿。已认识到造成出生体重不足的许多危险因素,按重要性排列为:产妇体重低、产妇血红蛋白低、产妇身高低、经产次数少、未成年母亲和产妇怀孕期间营养不良或不足。出生体重低的婴儿比出生体重正常的婴儿有更高的发病和死亡风险。本研究旨在探讨低出生体重儿的相关危险因素,为采取有效措施减轻低出生体重儿的负担提供依据。方法:这是一项基于医院的病例对照研究,于2008年1月1日至2010年5月30日在尼泊尔Kavre的Dhulikhel医院进行。对401例低出生体重儿母亲及相应年龄组的对照进行了危险因素分析。该研究的伦理批准来自KUSMS-机构研究委员会。数据分析采用SPSS 10.0。结果:对401例低出生体重儿及等量正常出生体重儿资料进行分析。本研究中LBW的发生率为11.07%。女性(n=236)比男性(n=165)婴儿更常见LBW。然而,该差异在统计学上不显著。在病例组和对照组中,母亲血红蛋白(p<0.001)、母亲身高(p<0.001)、母亲体重增加(p<0.0001)、ANC就诊次数(p<0.0001)具有统计学意义。然而,在种族、怀孕期间的营养、产次和母亲年龄方面,这种关联是微不足道的。民族、孕期营养、母亲年龄和产次对LBW无统计学意义。结论:LBW是发展中国家的一个普遍问题,是围产儿死亡率和发病率的重要因素。发现母亲身高、血红蛋白、总体重增加和ANC访视是导致LBW DOI的重要风险因素:http://dx.doi.org/10.3126/joim.v32i3.4959医学研究所杂志,2010年12月; 32:3 39-42
Introduction : WHO defines low birth weight (LBW) as a birth weight less than 2500 grams. Almost a third of the newborn in South East Asia Region is a low birth weight baby. Many risk factors contributing to LBW have been recognized, which in order of importance are low maternal weight, low maternal hemoglobin, low maternal height, primi-parity, adolescent mother and poor or inadequate maternal nutrition during pregnancy. Low birth weight babies have a higher risk of morbidity and mortality than an infant of normal birth weight. The present study was carried out to explore the associated risk factors of low birth weight which will be beneficial to undertake effective measures to reduce the burden of the low birth weight. Methods : This was a hospital based case control study conducted in Dhulikhel hospital, Kavre, Nepal from Jan 1st 2008 to 30th May 2010. A total of 401 cases and an equal number of age matched controls were taken to assess the different risk factors of the mother for LBW babies. Ethical approval for the study was taken from KUSMS-Institutional research committee. Data analysis was done using SPSS version 10.0. Results : Data of 401 LBW and equal number of normal birth weight babies were analyzed. The incidence of LBW in this study was 11.07%. LBW was more common in female (n=236) than in male (n=165) babies. However this difference was statistically insignificant. Among the case and the control group, maternal hemoglobin (p<0.001), maternal height (p<0.001), maternal weight gain (p<0.0001), number of ANC visits (p<0.0001) were statistically significant. However with regards to ethnicity, nutrition during pregnancy, parity and age of the mother the association were insignificant. Ethnical group, nutrition during pregnancy, age of mother and parity was found to be statically insignificant for LBW Conclusions : LBW is a common problem of the developing world, which is an important factor for perinatal mortality and morbidity. Maternal height, hemoglobin, total weight gain and ANC visit were found to be the significant risk factors contributing to LBW DOI: http://dx.doi.org/10.3126/joim.v32i3.4959 Journal of Institute of Medicine , December, 2010; 32:3 39-42