Carotid endarterectomy for asymptomatic patients. Assessing results of a quantitative synthesis.

Carotid endarterectomy for asymptomatic patients. Assessing results of a quantitative synthesis.
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对无症状患者进行颈动脉内膜切除术。

DOI:
10.1017/s0266462300004505
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发表时间:
1993
影响因子:
3.2
通讯作者:
Holloway,JJ
Holloway,JJ
中科院分区:
医学4区
文献类型:
--
作者:
Langenbrunner,JC;Wortman,PM;Yeaton,WH;Holloway,JJ

文献摘要

相似文献

尽管有数百项已发表的研究和最近的随机试验,但对于无症状患者的颈动脉内膜切除术(CE)手术仍然存在争议。安全性和有效性的评估使用了一种源自荟萃分析的定量综合方法和“关键倍增器”推理方法。此外,多变量分析显示,使用外科分流术可以进一步改善CE的预后。对方法的“确认性”和“探索性”价值进行了检验。
Carotid endarterectomy (CE) surgery for asymptomatic patients remains controversial despite hundreds of published studies and recent randomized trials. Safety and efficacy are assessed using a quantitative synthesis method derived from meta-analysis and a “critical multiplist” inference approach. In addition, multivariate analyses reveal that use of a surgical shunt could further improve CE outcomes. Methods are examined for both their “confirmatory” and “exploratory” value.