ASCORBIC-ACID REQUIREMENTS FOR SMOKERS - ANALYSIS OF A POPULATION SURVEY

ASCORBIC-ACID REQUIREMENTS FOR SMOKERS - ANALYSIS OF A POPULATION SURVEY
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DOI:
10.1093/ajcn/53.6.1466
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发表时间:
1991-06-01
影响因子:
7.1
通讯作者:
HOFFMANN, R
HOFFMANN, R
中科院分区:
医学1区
文献类型:
--
作者:
SCHECTMAN, G;BYRD, JC;HOFFMANN, R

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最近,吸烟者的抗坏血酸推荐膳食摄入量(RDA)从60毫克增加到100毫克。为了确定这一新的吸烟者RDA是否足以将低血清抗坏血酸浓度(LoC)降低到与不吸烟者相同的浓度,我们分析了1976-1980年国家健康和营养检查调查中11582名成年受访者的膳食摄入量和血清抗坏血酸浓度。比较摄入不同剂量AA的吸烟者与AA摄入量超过RDA(60 Mg)的非吸烟者的血清AA浓度及发生LOC(血清抗坏血酸水平&23 mU/L)的危险性。在保持AA摄入量为60、100和150毫克的吸烟者中,血清AA浓度降低,LOC风险增加。只有每天摄入200 mg AA的吸烟者的血清抗坏血酸浓度和LOC风险与非吸烟者达到RDA的水平相当。
The recommended dietary allowance (RDA) of ascorbic acid for smokers was recently increased from 60 to 100 mg. To determine whether this new RDA for smokers is sufficient to reduce the risk of low serum ascorbic acid (AA) concentrations (LoC) to the same concentration as nonsmokers, we analyzed the dietary intakes and serum concentrations of AA in 11 582 adult respondents in the National Health and Nutrition Examination Survey (1976-1980). Serum AA concentrations and the risk of LoC (serum ascorbic acid levels < 23 mu-mol/L) for smokers consuming different amounts of AA were compared with those for nonsmokers whose AA intake exceeded the RDA (60 mg). Serum AA concentrations were reduced, and risk of LoC increased, in smokers maintaining AA intakes > 60, 100, and 150 mg. Only smokers consuming > 200 mg AA/d had serum ascorbate concentrations and risk of LoC equivalent to nonsmokers meeting the RDA.