Crossprotection against nontuberculous mycobacterial infections by Mycobacterium tuberculosis memory immune T lymphocytes
Crossprotection against nontuberculous mycobacterial infections by Mycobacterium tuberculosis memory immune T lymphocytes
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结核分枝杆菌记忆免疫T淋巴细胞对非结核分枝杆菌感染的交叉保护作用
DOI：
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发表时间：
1986
影响因子：
15.3
通讯作者：
Frank M. Collins
中科院分区：
文献类型：
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作者：
I. Orme;Frank M. Collins
用结核分枝杆菌特异性记忆免疫T淋巴细胞过继免疫T细胞缺陷的受体小鼠，使这些动物对同种感染和三种非结核分枝杆菌的抵抗力显著增强。因此，这些结果支持这样的假设，即与产生保护性细胞免疫相关的四株分枝杆菌所拥有的抗原决定簇是相同的或密切交叉反应的。
Adoptive immunization of T cell-deficient recipient mice with M. tuberculosis-specific memory immune T lymphocytes conferred upon these animals the ability to express significantly enhanced resistance both to the homologous infection, and to three strains of nontuberculous mycobacteria. These results support the hypothesis, therefore, that antigenic determinants possessed by the four mycobacterial strains that are relevant to the generation of protective cellular immunity are identical or closely crossreactive.
卡介苗接种对小鼠对非结核分枝杆菌感染的预防作用。
DOI：
10.1016/0041-3879(85)90076-5
发表时间：
1985
期刊：
Tubercle
影响因子：
--
作者：
Orme,IM;Collins,FM
通讯作者：
Collins,FM