Are Mobile Persons With Parkinson Disease Necessarily More Active?
Are Mobile Persons With Parkinson Disease Necessarily More Active?
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DOI：
10.1097/npt.0000000000000362
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发表时间：
2021-10-01
期刊：
影响因子：
--
通讯作者：
Ellis TD
中科院分区：
文献类型：
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作者：
Zajac JA;Cavanaugh JT;Baker T;Colón-Semenza C;DeAngelis TR;Duncan RP;Fulford D;LaValley M;Nordahl T;Rawson KS;Saint-Hilaire M;Thomas CA;Earhart GM;Ellis TD
帕金森病（PD）患者的步行活动对于预防功能下降很重要。步行活动对PD患者家庭和社区流动性的贡献知之甚少。从一项随机对照PD试验中分析横断面基线数据（n=69）。生活空间评估（LSA）量化了家庭和社区流动性的五个扩展级别的程度，频率和独立性，产生个人分项得分和总分。两个额外的总和分数用于表示在（1-3级）和超出（4-5级）邻域限制内的移动性。加速度计测量了七天的步行活动。回归和相关性分析评估了每日步数和移动性评分之间的关系。其次，Mann-Whitney U检验比较了活动组和久坐组之间的移动性评分差异。步行活动对1-3级总分（β=.001，p=.004）有显著贡献，但对4-5级总分（β=.001，p=.33）或总分（β=.002，p=.07）无显著贡献。步行活动与1级（ρ= 0.336，p= 0.005）、2级（ρ= 0.307，p= 0.010）和3级（ρ= 0.314，p= 0.009）分项评分显著相关。活动组和久坐组之间只有1-3级总分（p= 0.030）有显著差异。在社区以外表现出更大流动性的PD患者不一定更活跃;步行活动对家庭和社区流动性的贡献更大。与LSA总分相比，1-3级总分可能是评估步行活动变化影响的更有用的参与水平指标。从作者那里获得更多的见解（见补充数字内容1）
Walking activity in persons with Parkinson disease (PD) is important for preventing functional decline. The contribution of walking activity to home and community mobility in PD is poorly understood. Cross-sectional baseline data (n=69) were analyzed from a randomized controlled PD trial. The Life-Space Assessment (LSA) quantified the extent, frequency, and independence across five expanding levels of home and community mobility, producing individual subscores and a total score. Two additional summed scores were used to represent mobility within (Levels 1-3) and beyond (Levels 4-5) neighborhood limits. An accelerometer measured walking activity for seven days. Regression and correlation analyses evaluated relationships between daily steps and mobility scores. Mann-Whitney U tests secondarily compared differences in mobility scores between active and sedentary groups. Walking activity contributed significantly to the summed Level 1-3 score (β=.001, p=.004) but not to the summed Level 4-5 (β=.001, p=.33) or total (β=.002, p=.07) scores. Walking activity was significantly related to Level 1 (ρ=.336, p=.005), Level 2 (ρ=.307, p=.010), and Level 3 (ρ=.314, p=.009) subscores. Only the summed Level 1-3 score (p=.030) was significantly different between active and sedentary groups. Persons with PD who demonstrated greater mobility beyond the neighborhood were not necessarily more active; walking activity contributed moreso to home and neighborhood mobility. Compared to LSA total score, the Level 1-3 summed score may be a more useful participation-level measure for assessing the impact of changes in walking activity. for more insight from the authors (see Supplemental Digital Content 1)