CHARACTERIZING AN AGAR/GELATIN PHANTOM FOR IMAGE GUIDED DOSING AND FEEDBACK CONTROL OF HIGH-INTENSITY FOCUSED ULTRASOUND
CHARACTERIZING AN AGAR/GELATIN PHANTOM FOR IMAGE GUIDED DOSING AND FEEDBACK CONTROL OF HIGH-INTENSITY FOCUSED ULTRASOUND
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DOI：
10.1016/j.ultrasmedbio.2012.09.016
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发表时间：
2013-02-01
影响因子：
2.9
通讯作者：
Sekins, K. Michael
中科院分区：
文献类型：
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作者：
Dunmire, Barbrina;Kucewicz, John C.;Sekins, K. Michael
评价了琼脂/明胶体模的温度依赖性。目的是预测材料对高强度聚焦超声（HIFU）的性能响应，以开发超声引导剂量和靶向反馈。在制造后的3周内，从20 ℃到70 ℃检查衰减、声速、剪切模量和热性能随温度的变化。衰减随温度下降的功率因数为0.15。热导率、扩散率和比热均随温度线性增加，总变化分别约为16%、10%和6%。声速对温度的依赖性呈抛物线状，与水的情况类似。最初，剪切模量不可逆地下降，甚至在温度的轻微增加。随着时间的推移，凝胶在适度加热下保持其室温剪切模量。在制造后2周内实现了稳定的体模，其具有高达近55 ℃的准可逆材料特性。（电子邮件：mrbean@u.washington.edu）（C）2013年世界医学和生物学超声联合会。
The temperature dependence of an agar/gelatin phantom was evaluated. The purpose was to predict the material property response to high-intensity focused ultrasound (HIFU) for developing ultrasound guided dosing and targeting feedback. Changes in attenuation, sound speed, shear modulus and thermal properties with temperature were examined from 20 degrees C to 70 degrees C for 3 weeks post-manufacture. The attenuation decreased with temperature by a power factor of 0.15. Thermal conductivity, diffusivity and specific heat all increased linearly with temperature for a total change of approximately 16%, 10% and 6%, respectively. Sound speed had a parabolic dependence on temperature similar to that of water. Initially, the shear modulus irreversibly declined with even a slight increase in temperature. Over time, the gel maintained its room temperature shear modulus with moderate heating. A stable phantom was achieved within 2 weeks post-manufacture that possessed quasi-reversible material properties up to nearly 55 degrees C. (E-mail: mrbean@u.washington.edu) (C) 2013 World Federation for Ultrasound in Medicine & Biology.