Noisy activation kinetics induces bursting in the Huber-Braun neuron model

Noisy activation kinetics induces bursting in the Huber-Braun neuron model
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噪声激活动力学导致 Huber-Braun 神经元模型中的爆发

DOI:
10.1140/epjst/e2010-01284-1
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发表时间:
2010
期刊:
The European Physical Journal Special Topics
影响因子:
--
通讯作者:
U. Feudel
U. Feudel
中科院分区:
--
文献类型:
--
作者:
C. Finke;S. Postnova;E. Rosa;J. Freund;M. Huber;K. Voigt;F. Moss;H. Braun;U. Feudel

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摘要 我们研究了一个生理上现实的实现内部随机性的四维Hodgkin-Huxley型模型的哺乳动物冷受体。我们表明,在一个确定性的紧张性放电制度,这种随机性可以驱动神经元进入一个复杂的突发行为的状态。这种效果背后的机制的解释是在相空间动力学。
Abstract We study a physiologically realistic implementation of internal stochasticity in a four-dimensional Hodgkin-Huxley type model of mammalian cold receptors. We show that in a deterministically tonic firing regime, this stochasticity can drive the neuron into a state of complex bursting behaviour. An explanation of the mechanism behind this effect is given in terms of phase space dynamics.