Eicosapentaenoic acid/arachidonic acid ratio in Japanese junior high school students
Eicosapentaenoic acid/arachidonic acid ratio in Japanese junior high school students
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DOI：
10.1111/ped.14898
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发表时间：
2022-01-01
影响因子：
1.4
通讯作者：
Nishimura，Rimei
中科院分区：
文献类型：
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作者：
Takahashi，Hiroshi;Sano，Hironari;Nishimura，Rimei
研究背景本流行病学研究调查了日本九年级学生的二十碳五烯酸/花生四烯酸比率（eicosapentaenoic acid/arachidonic acid ratio，ECAP）和二十二碳六烯酸/花生四烯酸比率（docosahexaenoic acid/ arachidonic acid ratio，DAR）。所有参与者都在年度健康检查期间进行评估，以确定他们的年龄和DAR。使用Mann-Whitney检验比较男孩和女孩之间的所有数据。斯皮尔曼的等级相关系数被用来描述的强度之间的相关性，DAR，和相关的parameters.ResultsThe中位数（最小，最大）的平均值和DAR的所有参与者分别为0.13（0.05，0.46）和0.47（0.25，0.84），分别。男、女生的平均年龄分别为0.12（0.05，0.46）和0.13（0.06，0.27），差异无统计学意义（P= 0.375）。DAR无显著差异（P= 0.125）。BMI与甘油三酯、体重指数、稳态模型评估值呈显著正相关，与HbA 1c呈显著负相关（r=-0.209，P = 0.006）。相反，DAR和任何parameters.ConclusionsThis之间没有显着的相关性是第一个流行病学研究调查的使用人口为基础的队列的日本青少年。在日本，男孩/女孩的比值为0.12（0.05，0.46）/0.13（0.06，0.27）。研究结果表明，健康饮食的儿童通常平均血糖水平较低。
BackgroundThis epidemiological study investigated the eicosapentaenoic acid/arachidonic acid ratio (EAR) and docosahexaenoic acid/ arachidonic acid ratio (DAR) in ninth‐graders in Japan.MethodsA total of 175 ninth‐grade children from Tsunan Town (115 boys and 60 girls) were enrolled in the study between 2015 and 2017. All participants were assessed during annual health checkups to determine their EAR and DAR. All data were compared between boys and girls using the Mann–Whitney test. Spearman's rank correlation coefficient was used to describe the strengths of correlations between the EAR, DAR, and relevant parameters.ResultsThe median (minimum, maximum) EAR and DAR of all participants were 0.13 (0.05, 0.46) and 0.47 (0.25, 0.84), respectively. There was no significant difference in the EAR between boys and girls at 0.12 (0.05, 0.46) and 0.13 (0.06, 0.27) (P= 0.375), respectively. The DAR was not significantly different (P= 0.125). There was a significant positive correlation between EAR and triglyceride, body mass index, and homeostasis model assessment but a significantly negative correlation with HbA1c (r= −0.209,P= 0.006). In contrast, there was no significant correlation between DAR and any parameters.ConclusionsThis is the first epidemiological study investigating the EAR using a population‐based cohort of Japanese adolescents. The EAR in boys/girls in Japan is 0.12 (0.05, 0.46)/0.13 (0.06, 0.27). The study results suggest that children with a healthy diet may generally have a lower average blood glucose level.