Femtosecond laser-assisted posterior lamellar keratoplasty - Initial studies of surgical technique in eye bank eyes
Femtosecond laser-assisted posterior lamellar keratoplasty - Initial studies of surgical technique in eye bank eyes
复制标题
DOI：
10.1016/j.ophtha.2004.06.037
复制
发表时间：
2005-01-01
期刊：
影响因子：
13.7
通讯作者：
Juhasz, T
中科院分区：
文献类型：
--
作者：
Soong, HK;Mian, S;Juhasz, T
目的：目的：完善飞秒激光辅助切削板层角膜盘在后板层角膜移植术中的应用技术。设计：实验研究。方法：采用飞秒激光对20例眼库球形角膜和9例眼库角巩膜扣状角膜进行后板层界面和环钻（侧）切削。激光参数为能量7.4+/-0.1 μ J（层状切割）和8.7+/-0.1 muJ（环钻切割），光斑尺寸2.4 μ m，发射速率15 kHz，环钻直径6.0 ~ 8.0 mm。用数字测微计测量切除的角膜盘的厚度，并与根据激光治疗参数和术前超声测厚计计算的值进行比较。读数。通过光学显微镜和扫描电子显微镜检查切割表面。在球形手术中，在激光治疗后通过周边角膜中的刀片切口从眼睛中取出角膜盘。在角巩膜纽扣中，在人工前房装置上进行激光治疗后，用镊子将后盘从角膜上剥离。在模拟移植中，将切下的角膜盘放置在7个球的后基质床中。结果：飞秒激光成功地在角膜中进行后板层和环钻切割。切割表面具有非常好的质量，具有直的正交边缘，尽管层状基质表面具有温和的灰泥纹理。3个球形片层表面呈浅的同心圆状脊。切除的光盘的测量厚度为55+/-61妈妈厚比术前的预测values.Conclusions：这些初步研究表明，飞秒激光可以使非机械切割后板层角膜移植术相对容易和可靠，从而促进在这项手术中最技术上困难的一步。(C)2005年，美国眼科学会。
Objective: To perfect the technique of femtosecond laser-assisted cutting of the lamellar corneal disc in posterior lamellar keratoplasty.Design: Experimental study.Methods: The femtosecond laser was used to make the posterior corneal lamellar interface and trephine (side) cut in 20 eye bank globes and 9 eye bank corneoscleral buttons. Laser parameters were energy 7.4+/-0.1 muJ (lamellar cut) and 8.7+/-0.1 muJ (trephination cut), spot size 2.4 mum, firing rate 15 kHz, and trephination diameter 6.0 to 8.0 mm. The thicknesses of the excised corneal discs were measured with a digital micrometer and compared with values calculated from the laser treatment parameters and the preoperative ultrasound pachymetric readings. The cut surfaces were examined by light microscopy and scanning electron microscopy. In globes, the corneal disc was removed from the eye after laser treatment through a blade incision in the peripheral cornea. In corneoscleral buttons, the posterior disc was peeled off the cornea with forceps after laser treatment on an artificial anterior chamber device. In simulated transplantation, the excised corneal disc was placed into the posterior stromal bed in 7 globes.Results: The femtosecond laser was successful in making posterior lamellar and trephination cuts in cornea. The cut surfaces were of very good quality with straight, orthogonal edges, albeit with a mild stucco texture of the lamellar stromal surfaces. In 3 globes, the lamellar surface showed shallow concentric ridges. The measured thickness of the excised discs was 55+/-61 mum thicker than the preoperatively predicted values.Conclusions: These preliminary studies show that the femtosecond laser can make nonmechanical cuts for posterior lamellar keratoplasty with relative ease and reliability, thus facilitating the most technically difficult step in this surgery. (C) 2005 by the American Academy of Ophthalmology.