Pilot study on the use of tourniquet: a risk factor for pulmonary thromboembolism after total knee arthroplasty?

Pilot study on the use of tourniquet: a risk factor for pulmonary thromboembolism after total knee arthroplasty?
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DOI:
10.1016/j.thromres.2004.08.018
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发表时间:
2005-01-01
影响因子:
7.5
通讯作者:
Aoyagi, K
Aoyagi, K
中科院分区:
医学3区
文献类型:
--
作者:
Nishiguchi, M;Takamura, N;Aoyagi, K

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全膝关节置换术(TKA)后使用止血带发生肺血栓栓塞(PTE)的风险仍有争议。在这项研究中,我们确定了血浆D-二聚体是否可以用作PTE的标志物,以及术中使用止血带是否是TKA后症状性PTE的风险因素。我们根据(i)手术方法(单侧/双侧)和(ii)术中使用充气止血带(有/无)将86例接受初次TKA的患者(12例男性和74例女性)分为4组。在术前和术后第1天测量血浆D-二聚体值。“D1值”定义为术后和术前血浆D-二聚体水平之间的差异。我们通过氧饱和度(SAT)和肺动脉造影监测,确定了症状性PTE的“D1值”临界值。有PTE症状者的D1值高于无症状者(p
The risk of pulmonary thromboembolism (PTE) after total knee arthroplasty (TKA) with, tourniquet is still controversial. In this study, we determined whether plasma D-dimer could be used, as a marker of PTE, and whether intraoperative use of tourniquet is a risk factor for symptomatic PTE after TKA. We divided 86 patients (12 mates and 74 females) who underwent primary TKA into four groups based on (i) operation method (unilateral/bilateral) and (ii) use of pneumatic tourniquet during surgery (with/without). Plasma D-dimer values were measured preoperatively and on Day 1 postoperatively. ''D1-value" was defined as the difference between postoperative and preoperative plasma D-dimer levels. We determined the cut off level of "D1-value" for symptomatic PTE, monitored by O-2 saturation (SAT) and lung scintigraphy. "D1-values" for patients with PTE symptoms were higher than those without symptoms (p