Neural correlates of individual differences related to appetite

Neural correlates of individual differences related to appetite
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DOI:
10.1016/j.physbeh.2009.04.001
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发表时间:
2009-07-14
影响因子:
2.9
通讯作者:
Coletta, Maria
Coletta, Maria
中科院分区:
医学3区
文献类型:
--
作者:
Lowe, Michael R.;van Steenburgh, Jason;Coletta, Maria

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使用神经影像技术来比较正常体重和肥胖个体可以揭示很多有关肥胖的病理生理状态的信息,但这种比较并不能告诉我们什么使一些正常体重个体容易患肥胖症或肥胖个体之间的重要个体差异。因此,当前的综述回顾了关于个体差异测量的神经影像学研究,这些研究可以阐明这些重要的主题。在介绍了接近奖励刺激的动机本质的三种神经心理学模型之后,对冲动、渴望、暴食、克制饮食和去抑制饮食测量的神经影像学研究进行了回顾。尽管针对与食欲相关的大脑活动的个体差异测量的神经影像学研究还处于起步阶段,但现有研究表明,此类研究可以丰富对饮食失调和肥胖的理解、预防和治疗。 (C) 2009 Elsevier Inc. 保留所有权利。
Using neuroimaging technologies to compare normal weight and obese individuals can reveal much about the pathophysiological state of obesity but such comparisons tell us little about what makes some normal weight individuals susceptible to obesity or about important individual differences amongst obese individuals. The current review therefore reviews neuroimaging research on individual difference measures that can illuminate these important topics. After introducing three neuropsychological models of the nature of motivation to approach rewarding stimuli, neuroimaging research on measures of impulsivity, craving, binge eating, restrained eating and disinhibited eating is reviewed. Although neuroimaging research on individual differences measures of brain activity related to appetite is in its infancy, existing studies suggest that such research could enrich the understanding, prevention and treatment of disordered eating and obesity. (C) 2009 Elsevier Inc. All rights reserved.