The natural history of patients with carotid stenosis
The natural history of patients with carotid stenosis
复制标题
颈动脉狭窄患者的自然史
DOI：
--
复制
发表时间：
2002
影响因子：
--
通讯作者：
H. Sillesen
中科院分区：
文献类型：
--
作者：
H. Sillesen
动脉粥样硬化是一种影响全身循环系统的全身性疾病。因此，患有颈动脉粥样硬化的患者不仅有中风的风险，而且还有该疾病的其他表现，即血管性死亡、心肌梗死等。到目前为止，评估该患者组治疗效果的干预试验，即通过手术切除颈动脉病变，集中在病变狭窄程度上。然而，许多其他因素可能也很重要：病变的局部因素（形态、狭窄程度）、血流动力学因素（侧支代偿）和全身因素（临床症状、伴随疾病、风险因素控制）。最近的研究结果表明，斑块形态（成分和结构）可能比狭窄程度更重要，可以推测，如果目前的指示颈动脉内膜切除术是最佳的。
Atherosclerosis is a systemic disease affecting the circulatory system throughout the body. Thus, patients with atherosclerosis of the carotid arteries are not only at risk of stroke but also of other manifestations of the disease, i.e. vascular death, myocardial infarction etc. So far, intervention trials evaluating the effect of treatment of this patient group, i.e. by surgical removal of the carotid lesion, has focussed on degree of stenosis of the lesion. However, many other factors may be of importance: local factors of the lesion (morphology, degree of stenosis), hemodynamic factors (collateral compensation) and systemic factors (clinical symptoms, accompanying diseases, risk factor control). Recent findings suggest that plaque morphology (composition and structure) may be of greater importance than the degree of stenosis and it may be speculated if current indications for carotid endarterectomy are optimal.
影响因子：
158.5
作者：
CRIQUI, MH;LANGER, RD;BROWNER, D
通讯作者：
BROWNER, D
影响因子：
19.7
作者：
Polak, JF;Shemanski, L;Reid, C
通讯作者：
Reid, C