Stiffness changes of the cupula associated with the mechanics of hair cells in the fish lateral line.
Stiffness changes of the cupula associated with the mechanics of hair cells in the fish lateral line.
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DOI：
10.1073/pnas.91.4.1549
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发表时间：
1994-02
影响因子：
11.1
通讯作者：
S. V. van Netten;S. Khanna
中科院分区：
文献类型：
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作者：
S. V. van Netten;S. Khanna
本文用激光外差干涉法测量了鱼侧线管中的杯状振动对管内流体运动的响应。结果表明，吸盘的机械输出/输入比依赖于刺激幅度，吸盘因此表现出非线性。非线性是由于毛束，因为它消失时，吸盘是从下面的毛细胞解耦。一个模型的cupular动力学，其中的毛细胞的门控弹簧的行为被纳入预测的非线性响应，是类似的测量，这表明cupula的非线性行为可能是由于打开和关闭的转导通道的毛细胞。
Cupular vibration in the lateral-line canal of fish was measured in response to motion of the fluid in the canal by laser-heterodyne interferometry. The results show that the mechanical output/input ratio of the cupula depends on the stimulus amplitude; the cupula thus behaves nonlinearly. The nonlinearity is due to the hair bundles, since it disappears when the cupula is uncoupled from the underlying hair cells. A model of cupular dynamics in which the behavior of the gating springs of the hair cells is incorporated predicts nonlinear responses that are similar to the measurements, suggesting that the nonlinear behavior of the cupula may be attributed to the opening and closing of the transduction channels of the hair cells.