PULMONARY ARTERIAL PRESSURES OF NEWBORN INFANTS BORN WITH EARLY AND LATE CLAMPING OF CORD
PULMONARY ARTERIAL PRESSURES OF NEWBORN INFANTS BORN WITH EARLY AND LATE CLAMPING OF CORD
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DOI：
10.1111/j.1651-2227.1966.tb17659.x
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发表时间：
1966-01-01
期刊：
影响因子：
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通讯作者：
GESSNER, IH
中科院分区：
文献类型：
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作者：
ARCILLA, RA;OH, W;GESSNER, IH
对32例正常足月新生儿进行了血流动力学研究。至11小时，探讨胎盘输血对新生儿出生后肺循环调节的影响。在10名婴儿中，在2至10秒内完成脐带夹紧。分娩后（早期钳夹），其他22例婴儿在脐动脉搏动停止后（晚期钳夹）进行。出于比较的目的，肺动脉压与相应的主动脉压以P/A平均压力比的形式相关，并且这些与2组受试者的年龄相关。观察到的肺动脉压在两组之间存在显著差异。在前9小时，晚期钳夹婴儿的肺动脉压约为主动脉压的90%。相反，早期钳夹婴儿的肺动脉压在第2小时时低至主动脉压的70%，在第4小时时接近50%。本文提出一种假设，即晚期钳夹婴儿的肺动脉压较高是由于肺毛细血管[长破折号]静脉充盈较大而导致肺血管收缩较大，这是最大胎盘输血后血容量较大的结果。
Hemodynamlc studies were conducted on 32 normal, full-term newborn infants, age 29 mln. to 11 hr., to determine the effect of placental transfusion upon the pulmonary circulatory adjustments after birth. In 10 infants, clamping of the cord was accomplished within 2 to 10 sec. after the delivery (early clamping), and In the other 22 Infants it was done after cessation of the umbilical arterial pulsations (late clamping). For comparative purposes, the pulmonary arterial pressures were related to the corresponding aortic pressure in the form of a P/A mean pressure ratio, and these were correlated with age in the 2 groups of subjects. The observed pulmonary arterial pressures in the 2 groups differed significantly. During the 1st 9 hr., the pulmonary pressures of the late-clamped Infants were approximately 90% that of the aortic. In contrast, those of the early-clamped Infants were as low as 70% of the aortic pressures by the 2nd hr. and nearly 50% by the 4th hr. A hypothesis Is presented that the higher pulmonary arterial pressures in the late-clamped infants is due to greater pulmonary vasoconstrictlon resulting from greater pulmonary capillary[long dash]venous filling, a consequence of the large blood volume following maximal placental transfusion.