Distance to Radiation Facility and Treatment Choice in Early-Stage Breast Cancer
Distance to Radiation Facility and Treatment Choice in Early-Stage Breast Cancer
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DOI：
10.1016/j.ijrobp.2015.12.020
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发表时间：
2016-03-15
影响因子：
7
通讯作者：
Perkins, Stephanie M.
中科院分区：
文献类型：
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作者：
Acharya, Sahaja;Hsieh, Samantha;Perkins, Stephanie M.
目的：保乳治疗（BCT）是一种推荐的替代乳房切除术（MT）的早期乳腺癌。有限的放射治疗（RT）可能会导致更高的MT率。我们评估了距离最近的RT设施和MT的使用之间的关联，在一个现代队列的women.Methods和材料：妇女与0-II期乳腺癌符合BCT诊断从2004年至2010年确定从佛罗里达癌症数据系统（FCDS）。计算从患者普查区到最近的RT设施普查区的距离。多变量逻辑回归分析用于确定解释变量，影响MT use.Results：27,489合格的妇女，32.1%（n=8841）进行MT，67.8%（n=18,648）进行BCS。32%的患者居住在距离RT设施> 5英里的人口普查区域。MT的使用随着距离RT设施距离的增加而增加（5至< 15英里时为31.1%，15至< 40英里时为34.9%，>= 40英里时为51%，P
Purpose: Breast-conserving therapy (BCT) is a recommended alternative to mastectomy (MT) for early-stage breast cancer. Limited access to radiation therapy (RT) may result in higher rates of MT. We assessed the association between distance to the nearest RT facility and the use of MT, in a modern cohort of women.Methods and Materials: Women with stage 0-II breast cancer eligible for BCT diagnosed from 2004 to 2010 were identified from the Florida Cancer Data System (FCDS). Distances from patient census tracts to the nearest RT facility census tract were calculated. Multivariate logistic regression was used to identify explanatory variables that influenced MT use.Results: Of the 27,489 eligible women, 32.1% (n=8841) underwent MT, and 67.8% (n=18,648) underwent BCS. Thirty-two percent of patients lived in a census tract that was>5miles from an RT facility. MT use increased with increasing distance to RT facility (31.1% at 5 to< 15 miles, 34.9% at 15 to< 40 miles, and 51% at >= 40 miles, P