Na/K-ATPase Signaling and Salt Sensitivity: The Role of Oxidative Stress.
Na/K-ATPase Signaling and Salt Sensitivity: The Role of Oxidative Stress.
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DOI：
10.3390/antiox6010018
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发表时间：
2017-03-02
期刊：
影响因子：
--
通讯作者：
Shapiro JI
中科院分区：
文献类型：
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作者：
Liu J;Yan Y;Nie Y;Shapiro JI
除了血压盐敏感性的遗传调节外，许多因素已被证明可调节肾钠处理，这有助于长期血压调节，并已被广泛综述。在这里，我们提出了我们的进展Na/K-ATP酶信号介导的钠重吸收在肾近端小管，从强心类固醇介导的活性氧（ROS）介导的Na/K-ATP酶信号，有助于实验盐敏感性。
Other than genetic regulation of salt sensitivity of blood pressure, many factors have been shown to regulate renal sodium handling which contributes to long-term blood pressure regulation and have been extensively reviewed. Here we present our progress on the Na/K-ATPase signaling mediated sodium reabsorption in renal proximal tubules, from cardiotonic steroids-mediated to reactive oxygen species (ROS)-mediated Na/K-ATPase signaling that contributes to experimental salt sensitivity.