INVIVO MEASUREMENT OF REGIONAL CEREBRAL HEMATOCRIT USING POSITRON EMISSION TOMOGRAPHY

INVIVO MEASUREMENT OF REGIONAL CEREBRAL HEMATOCRIT USING POSITRON EMISSION TOMOGRAPHY
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DOI:
10.1038/jcbfm.1984.47
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发表时间:
1984-01-01
影响因子:
6.3
通讯作者:
JONES, T
JONES, T
中科院分区:
医学1区
文献类型:
--
作者:
LAMMERTSMA, AA;BROOKS, DJ;JONES, T

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A method is described for measuring the regional cerebral-to-large vessel hematocrit ratio using inhalation of C-11-labeled carbon monoxide and the i.v. injection of C-11-labeled methyl-albumin in combination with positron emission tomography. The mean value in a series of 9 subjects was 0.69. This is .apprx. 20% lower than the value of 0.85 previously reported. Previous measurements of regional cerebral blood volume using a hematocrit ratio of 0.85 will have underestimated the value of regional cerebral blood volume by 20%.