Metastasectomy for Stage IV Colorectal Cancer

Metastasectomy for Stage IV Colorectal Cancer
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DOI:
10.1007/dcr.0b013e3181dcadbc
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发表时间:
2010-07-01
影响因子:
3.9
通讯作者:
Dunn, Kelli Bullard
Dunn, Kelli Bullard
中科院分区:
医学2区
文献类型:
--
作者:
Mahmoud, Najjia;Dunn, Kelli Bullard

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转移性结直肠癌传统上被认为是不可治愈的。然而,在过去的30年里,切除小体积肝脏疾病在某些情况下被认为是有益的。最近,孤立性肺转移瘤的切除术已被证明可以为精心挑选的患者提供长期生存。切除转移到更不常见的部位(卵巢,脑,腹腔)是更有争议的,然而,回顾性数据表明,少数患者可以治愈切除这些肿瘤。在这篇文章中,我们回顾的历史和现状,直肠切除术在第四期结直肠癌。
Metastatic colorectal cancer traditionally has been considered incurable. Over the past 3 decades, however, resection of low-volume hepatic disease has been recognized as beneficial in some cases. More recently, resection of isolated pulmonary metastases has been shown to offer long-term survival in carefully selected patients. Resection of metastases to more unusual sites (ovary, brain, peritoneal cavity) is more controversial; nevertheless, retrospective data suggest that a few patients may be cured with resection of these tumors. In this article, we review the history and current status of metastasectomy in stage IV colorectal cancer.