Running exercise strengthens the intervertebral disc.
Running exercise strengthens the intervertebral disc.
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DOI：
10.1038/srep45975
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发表时间：
2017-04-19
影响因子：
4.6
通讯作者：
Rantalainen T
中科院分区：
文献类型：
--
作者：
Belavý DL;Quittner MJ;Ridgers N;Ling Y;Connell D;Rantalainen T
目前还没有证据表明椎间盘（IVD）可以对人类的运动做出积极的反应。一些作者认为，人类的IVD代谢太慢，无法在人类寿命内对运动做出合成代谢反应。在这里，我们表明，男性和女性的长期跑步运动与更好的IVD组成（水化和蛋白多糖含量）和IVD肥大相关。通过对身体活动的定量评估，我们进一步发现，快速行走和慢速跑步（2 m/s）时的加速度与IVD特征呈正相关，但高冲击任务、低强度行走或静态位置与此无关。这些发现代表了人类运动有益于IVD的第一个证据，并为特定运动方案可能改善脊柱中IVD材料特性的概念提供了支持。我们预计，我们的研究结果将是一个起点，以更好地定义运动方案和身体活动概况的IVD在人类中的支持。
There is currently no evidence that the intervertebral discs (IVDs) can respond positively to exercise in humans. Some authors have argued that IVD metabolism in humans is too slow to respond anabolically to exercise within the human lifespan. Here we show that chronic running exercise in men and women is associated with better IVD composition (hydration and proteoglycan content) and with IVD hypertrophy. Via quantitative assessment of physical activity we further find that accelerations at fast walking and slow running (2 m/s), but not high-impact tasks, lower intensity walking or static positions, correlated to positive IVD characteristics. These findings represent the first evidence in humans that exercise can be beneficial for the IVD and provide support for the notion that specific exercise protocols may improve IVD material properties in the spine. We anticipate that our findings will be a starting point to better define exercise protocols and physical activity profiles for IVD anabolism in humans.