A longitudinal comparative study of falls in persons with knee arthroplasty and persons with or at high risk for knee osteoarthritis.
A longitudinal comparative study of falls in persons with knee arthroplasty and persons with or at high risk for knee osteoarthritis.
复制标题
对膝关节置换术患者和膝骨关节炎患者或高风险患者跌倒的纵向比较研究。
DOI：
10.1093/ageing/afw126
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发表时间：
2016
期刊：
影响因子：
6.7
通讯作者：
Golladay,GregoryJ
中科院分区：
文献类型：
--
作者：
Riddle,DanielL;Golladay,GregoryJ
目的：我们确定了8年内膝关节骨关节炎（OA）患者或有风险患者以及接受膝关节置换术患者的单次和多次福尔斯的年患病率。我们还比较了年下降率之间的人与膝关节置换术，以确定是否下降率与膝关节置换术。Methodswe研究了4,200人骨关节炎模仿（OAI），美国国立卫生研究院资助的前瞻性研究的人45-79岁，从2004年至2012年进行。所有患者均患有膝关节OA或有发生膝关节OA的风险，但未接受膝关节置换术。手术组由413名接受膝关节置换术的患者组成。在每年的研究访视中评估了关键的跌倒风险因素。图示说明了单个和多个坠落轨迹。调整潜在的混杂因素的多项式回归比较下降率为那些与膝关节置换术和不。ResultsFall率轨迹为两个样本一般是平坦的，下降率相似。对于关节置换术样本，相对于早期和后期，在围手术期内跌倒率没有增加。在调整潜在的混杂因素后，没有发现关节置换术和非关节置换术样本之间的跌倒率有差异（P> 0.05）。临床医生不应认为接受膝关节置换术的患者在术前或术后发生福尔斯的风险高于膝关节OA患者或有膝关节OA风险的患者。
Objectiveswe determined the yearly prevalence of single and multiple falls in persons with or at risk of knee osteoarthritis (OA) and persons undergoing knee arthroplasty over an 8-year period. We also compared annual fall rates among persons with and without knee arthroplasty to determine if fall rates are associated with knee arthroplasty.Methodswe studied 4,200 persons from the Osteoarthritis Imitative (OAI), a National Institutes of Health funded prospective study of persons 45–79 years and conducted from 2004 to 2012. All either had knee OA or were at risk of developing knee OA but did not have knee arthroplasty. The surgical group comprised 413 persons who underwent knee arthroplasty. Key fall risk factors were assessed at yearly study visits. Graphical depictions illustrated single and multiple fall trajectories. Multinomial regression adjusted for potential confounders compared fall rates for those with and without knee arthroplasty.Resultsfall rate trajectories for the two samples were generally flat and fall rates were similar. For the arthroplasty sample, fall rates did not increase in the immediate perioperative period relative to earlier and later periods. No differences in fall rates were found among the arthroplasty and non-arthroplasty samples after adjustment for potential confounding (P> 0.05).Conclusionsfall rates were generally stable and similar over an 8-year period among persons with and without knee arthroplasty. Clinicians should not assume that persons undergoing knee arthroplasty are at greater risk for falls either before or after surgery as compared to persons with or at risk for knee OA.