Human Papillomavirus Vaccination Before 13 and 15 Years of Age: Analysis of National Immunization Survey Teen Data

Human Papillomavirus Vaccination Before 13 and 15 Years of Age: Analysis of National Immunization Survey Teen Data
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DOI:
10.1093/infdis/jiy682
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发表时间:
2019-09-01
影响因子:
6.4
通讯作者:
Omer, Sead B.
Omer, Sead B.
中科院分区:
医学2区
文献类型:
--
作者:
Bodnarczyk, Robert A.;Ellingson, Mallory K.;Omer, Sead B.

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人乳头瘤病毒(HPV)疫苗接种在美国使用不理想。免疫实践咨询委员会建议在13岁生日之前接种疫苗,而在15岁生日之前接种疫苗只需两剂。我们使用来自2016年全国免疫调查-青少年的提供者验证的疫苗接种数据估计了迄今为止HPV疫苗的青少年比例。只有16%的美国青少年在13岁之前完成了HPV疫苗接种,35%在15岁之前完成了HPV疫苗接种。随着整个青春期性活动的开始增加以及年轻疫苗接种者的免疫原性更高,在13岁生日之前接种疫苗可以更好地预防HPV相关癌症。
Human papillomavirus (HPV) vaccination is suboptimally used in the United States. Vaccination before the 13th birthday is recommended by the Advisory Committee on Immunization Practices and vaccination before the 15th birthday requires only 2 doses. We estimated the proportion of adolescents up to date for HPV vaccine using provider-verified vaccination data from the 2016 National Immunization Survey-Teen. Only 16% of US adolescents completed HPV vaccination before turning 13, and 35% completed HPV vaccination before turning 15. With sexual activity initiation increasing throughout adolescence and higher immunogenicity for younger vaccinees, vaccination before the 13th birthday can provide better protection against HPV-related cancers.