Bers-ERK Schwann cells coordinate nerve regeneration.

Bers-ERK Schwann cells coordinate nerve regeneration.
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Bers-ERK 雪旺细胞协调神经再生。

DOI:
10.1016/j.neuron.2012.02.002
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发表时间:
2012
期刊:
影响因子:
16.2
通讯作者:
Snider,WilliamD
Snider,WilliamD
中科院分区:
医学1区
文献类型:
--
作者:
Newbern,JasonM;Snider,WilliamD

文献摘要

相似文献

在本期《神经元》杂志中,Napoli等人(2012)证明了雪旺细胞中ERK/MAPK信号的升高是体内雪旺细胞去分化的关键触发因素。此外,作者表明,去分化的雪旺细胞有可能协调周围神经对损伤的反应。
In this issue ofNeuron, Napoli et al. (2012) demonstrate that elevated ERK/MAPK signaling in Schwann cells is a crucial trigger for Schwann cell dedifferentiation in vivo. Moreover, the authors show that dedifferentiated Schwann cells have the potential to coordinate much of the peripheral nerve response to injury.