First-pass perfusion computed tomography: Initial experience in differentiating adrenal adenoma from metastasis
First-pass perfusion computed tomography: Initial experience in differentiating adrenal adenoma from metastasis
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DOI：
10.1016/j.ejrad.2009.01.007
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发表时间：
2010-03-01
影响因子：
3.3
通讯作者：
Miao, Fei
中科院分区：
文献类型：
--
作者：
Qiao, Zhong-Wei;Xia, Chun-Mei;Miao, Fei
目的：目的：探讨CT灌注成像（PCT）在肾上腺腺瘤与转移瘤鉴别诊断中的价值。在这些患者中，21例被诊断为肾上腺腺瘤，其他患者被诊断为转移瘤。使用Advantage Windows工作站，使用CT灌注3.0软件（General Electric Medical Systems，密尔沃基，WI）生成血容量（By）、血流量（BF）、平均通过时间（MTT）和渗透性表面积产生（PS）的灌注图。结果：两组间BV、BF和PS等灌注参数差异有统计学意义，腺瘤组BV、BF和PS分别为12.18、97.51和21.73，显著高于转移瘤组（P
Objective: To differentiate adrenal adenoma from metastasis in patients using perfusion computed tomography (PCT) imaging.Methods: Thirty-two patients with adrenal masses underwent first-pass PCT imaging. Of these patients, twenty-one were diagnosed with adrenal adenoma, and the others with metastases. Perfusion maps of blood volume (By), blood flow (BF), mean transit time (MTT) and permeability surface-area production (PS) were generated with an Advantage Windows workstation using the CT perfusion 3.0 software (General Electric Medical Systems, Milwaukee, WI). Histopathologic sections immunostained for CD34 were quantitatively evaluated for microvessel density (MVD).Results: The perfusion parameters such as BV, BF and PS were statistically significant different between the two groups, with adenomas showing higher mean BV (12.18 versus 3.86), BF (97.51 versus 45.99) and PS (21.73 versus 10.93) compared with metastases (p