Mercury concentration and fish consumption in Taiwanese pregnant women
Mercury concentration and fish consumption in Taiwanese pregnant women
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DOI：
10.1111/j.1471-0528.2006.01142.x
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发表时间：
2007-01-01
影响因子：
5.8
通讯作者：
Han, B-C
中科院分区：
文献类型：
--
作者：
Hsu, C-S;Liu, P-L;Han, B-C
目的探讨台湾地区孕妇食用鱼类与母血、脐带血和胎盘组织中总汞含量的关系。设计横断面研究，以2004年7月至2005年3月在台湾台北市设立的医疗中心为研究对象，对65名2004年7月至2005年3月分娩的孕妇进行问卷调查。使用汞分析仪(Hiranuma HG-310，日立，日本)测量母亲血、脐带血和胎盘组织中的汞浓度。结果孕妇血、脐带血和胎盘组织中总汞平均浓度分别为9.1+/-0.40微克/L、10.0/-0.55微克/L和19.2+/-1.8 ng/g。89%的孕妇血汞含量超过美国国家研究委员会推荐值5.8微克/L。孕期食用鱼类与孕妇血和脐带血汞含量显著相关。结论孕妇血、脐血和胎盘组织总汞含量普遍超过推荐值，且孕妇每周吃鱼3次以上的孕妇汞含量更高。
Objective The aim of this study was to assess the relationship between fish consumption and total mercury concentration in maternal blood, umbilical cord blood, and placenta tissue of pregnant women in Taiwan.Design Cross-sectional study.Setting A medical centre in Taipei, Taiwan.Sample Sixty-five pregnant women delivered between July 2004 and March 2005.Methods We administered a questionnaire to each woman in the third trimester and collected blood samples and placenta tissue after delivery. Mercury concentrations in the maternal blood, cord blood and placenta tissue were measured using mercury analyser (Hiranuma HG-310, Hitachi, Japan). A dietitian calculated the quantity of fish consumed from the questionnaire.Main outcome measures The total mercury concentration in maternal blood, cord blood and placenta tissue.Results The mean total mercury concentration in maternal blood, cord blood and placenta tissue was 9.1 +/- 0.40 microgram/l, 10.0 +/- 0.55 microgram/l and 19.2 +/- 1.8 ng/g, respectively. Eighty-nine percent of the maternal blood mercury concentrations exceeded the US National Research Council recommended value of 5.8 microgram/l. Fish consumption while pregnant correlated significantly with maternal blood and cord blood mercury concentrations.Conclusions Total mercury concentrations of maternal blood, cord blood and placenta tissue commonly exceeded recommended values, and were higher in women who ate fish more than three times a week while pregnant.