Effects of occlusal stimuli on alveolar/jaw bone formation
Effects of occlusal stimuli on alveolar/jaw bone formation
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DOI：
10.1177/154405910708600107
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发表时间：
2007-01-01
影响因子：
7.6
通讯作者：
Soma, K.
中科院分区：
文献类型：
--
作者：
Shimomoto, Y.;Chung, C. J.;Soma, K.
众所周知，咬合会影响头面部复合体的生长和发育。然而，咬合功能减退或其恢复对牙槽骨和颌骨的形成和发育的影响尚不完全清楚。因此，本研究通过建立大鼠咬合功能减退/恢复模型，探讨咬合刺激与牙槽骨和颌骨生长的关系。在下颌第二磨牙双标记的额部切片上进行骨组织形态计量学分析，包括骨安置率和矿物质安置率。结果显示，与生长正常的动物相比，咬合功能减退对牙槽骨和颌骨的形成有显著的抑制作用(p<；0.05)。然而，咬合功能的恢复导致颌骨形成的增强。这些结果表明，在生长期内，咬合功能对牙槽骨和颌骨的形成有影响。
Occlusion is known to influence the growth and development of the craniofacial complex. However, the consequences of occlusal hypofunction, or its recovery, on the amount of formation and development of alveolar bone and the jaw are not fully understood. Therefore, the present study was designed to elucidate the relationship between the occlusal stimuli and alveolar and jaw bone growth by the use of a hypofunction/recovered occlusal function model in growing rats. Bone histomorphometric analyses, including bone apposition rate and mineral apposition rate, were evaluated in double-labeled frontal sections of mandibular second molars. Results showed that occlusal hypofunction significantly suppressed alveolar and jaw bone formation compared with that in animals growing normally (p < 0.05). However, recovered occlusal function induced an enhancement in jaw bone formation. These results indicate the influence of occlusal function on alveolar and jaw bone formation during the growth period.