"The one who doesn't take ART medication has no wealth at all and no purpose on Earth" - a qualitative assessment of how HIV-positive adults in Uganda understand the health and wealth-related benefits of ART.

"The one who doesn't take ART medication has no wealth at all and no purpose on Earth" - a qualitative assessment of how HIV-positive adults in Uganda understand the health and wealth-related benefits of ART.
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DOI:
10.1186/s12889-022-13461-w
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发表时间:
2022-05-27
期刊:
影响因子:
4.5
通讯作者:
Linnemayr, Sebastian
Linnemayr, Sebastian
中科院分区:
医学2区
文献类型:
--
作者:
Saya, Uzaib;MacCarthy, Sarah;Mukasa, Barbara;Wabukala, Peter;Lunkuse, Lillian;Wagner, Zachary;Linnemayr, Sebastian

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抗逆转录病毒疗法(ART)的预期寿命延长可能会影响艾滋病毒携带者(PLWH)未来的健康和财富。目前尚不清楚的是,PLWH在护理中如何看待坚持抗逆转录病毒治疗的好处,特别是在个人、家庭和结构层面的短期和长期改善健康和财富方面。了解对抗逆转录病毒治疗的面向未来的态度可能有助于政策制定者在考虑到短期和长期健康益处的情况下定制护理和治疗计划,以改善PLWH与艾滋病毒相关的结果。在这项定性研究中,我们对乌干达一家诊所的40名在护理中的PLWH进行了半结构化访谈,该样本参与了乌干达治疗依从性的随机临床试验(Clinicaltrials.gov:NCT03494777)。采访被逐字转录,并从卢甘达语翻译成英语。两位合著者独立审阅了成绩单,开发了详细的代码簿,在双码访谈上取得了93%的一致性,并使用归纳和演绎内容分析来分析数据。应用个人、家庭和结构层面的社会生态框架,我们考察了PLWH如何感知与ART相关的健康和财富利益。我们的发现揭示了PLWH所表达的抗逆转录病毒疗法的几个好处,不仅是短期的健康好处,还包括长期的经济好处。这些好处主要集中在长寿和身心健康方面,同时也在个人层面履行与自身有关的责任(特别是在积极的长期习惯和更努力工作的动力方面),在家庭层面与他人有关(例如改善与家人和朋友的关系),在与社会有关的结构层面(在减少污名、披露时更舒适和更高水平的公民责任方面)。PLWH考虑抗逆转录病毒治疗的短期和长期健康益处。旨在塑造艺术吸收和增加坚持的规划应强调艺术在各个层面上的更广泛好处。将这些好处直接纳入以临床为基础的艾滋病毒干预措施的设计中可能是有用的,特别是对于面临着增加用药依从性的相互竞争的利益的PLWH来说。这些好处最终可以帮助提供者和政策制定者更好地理解PLWH的决策,因为它与改善与艺术相关的结果有关。网上版载有补充材料,可在10.1186/s12889-022-13461-w查阅。
Increases in life expectancy from antiretroviral therapy (ART) may influence future health and wealth among people living with HIV (PLWH). What remains unknown is how PLWH in care perceive the benefits of ART adherence, particularly in terms of improving health and wealth in the short and long-term at the individual, household, and structural levels. Understanding future-oriented attitudes towards ART may help policymakers tailor care and treatment programs with both short and long-term-term health benefits in mind, to improve HIV-related outcomes for PLWH. In this qualitative study, we conducted semi-structured interviews among a subsample of 40 PLWH in care at a clinic in Uganda participating in a randomized clinical trial for treatment adherence in Uganda (clinicaltrials.gov: NCT03494777). Interviews were transcribed verbatim and translated from Luganda into English. Two co-authors independently reviewed transcripts, developed a detailed codebook, achieved 93% agreement on double-coded interviews, and analyzed data using inductive and deductive content analysis. Applying the social-ecological framework at the individual, household, and structural levels, we examined how PLWH perceived health and wealth-related benefits to ART. Our findings revealed several benefits of ART expressed by PLWH, going beyond the short-term health benefits to also include long-term economic benefits. Such benefits largely focused on the ability of PLWH to live longer and be physically and mentally healthy, while also fulfilling responsibilities at the individual level pertaining to themselves (especially in terms of positive long-term habits and motivation to work harder), at the household level pertaining to others (such as improved relations with family and friends), and at the structural level pertaining to society (in terms of reduced stigma, increased comfort in disclosure, and higher levels of civic responsibility). PLWH consider short and long-term health benefits of ART. Programming designed to shape ART uptake and increase adherence should emphasize the broader benefits of ART at various levels. Having such benefits directly integrated into the design of clinic-based HIV interventions can be useful especially for PLWH who face competing interests to increase medication adherence. These benefits can ultimately help providers and policymakers better understand PLWH’s decision-making as it relates to improving ART-related outcomes. The online version contains supplementary material available at 10.1186/s12889-022-13461-w.
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