New triterpene saponins from the roots of Acacia macrostachya (Mimosaceae)

New triterpene saponins from the roots of Acacia macrostachya (Mimosaceae)
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来自金合欢(含羞草科)根部的新三萜皂苷

DOI:
10.1080/09168451.2017.1390393
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发表时间:
2017
期刊:
Bioscience, biotechnology and biochemistry
影响因子:
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通讯作者:
B. Ngadjui
B. Ngadjui
中科院分区:
--
文献类型:
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作者:
Abdou Tchoukoua;T. Tabopda;Narandulam Usukhbayar;K. Kimura;Eunsang Kwon;Hiroyuki Momma;T. Koseki;Y. Shiono;B. Ngadjui

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从大穗金合欢根中分离出四种新的齐墩果烷型皂苷,大穗苷 A、B、C 和 D (1-4)。它们的结构在广泛的一维和二维核磁共振数据以及 HR-ESI-MS 分析的基础上得到了阐明。在每种化合物的浓度为 100 μM 时,没有一种测试化合物会导致 HL60 细胞的生长显着下降。从大穗金合欢中分离出四种新的齐墩果烷型皂苷。使用 1D 和 2D NMR 以及 HRESIMS 阐明了它们的结构。
Four new oleanane-type saponins, macrostachyaosides A, B, C, and D (1–4) were isolated from the roots of Acacia macrostachya. Their structures were elucidated on the basis of extensive 1D- and 2D-NMR data and HR-ESI-MS analyses. At concentrations of 100 μM of each compounds, none of the tested compounds caused a significant growth reduction against HL60 cells. Four new oleanane-type saponins were isolated from Acacia macrostachya. Their structures were elucidated using 1D and 2D NMR and HRESIMS.