Correlation between active and passive isometric force and intramuscular pressure in the isolated rabbit tibialis anterior muscle
Correlation between active and passive isometric force and intramuscular pressure in the isolated rabbit tibialis anterior muscle
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DOI：
10.1016/s0021-9290(02)00430-x
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发表时间：
2003-04-01
影响因子：
2.4
通讯作者：
Lieber, RL
中科院分区：
文献类型：
--
作者：
Davis, J;Kaufman, KR;Lieber, RL
本研究的目的是量化肌肉压力（IMP）和肌肉力量之间的关系，在等长收缩的兔胫骨前肌（TA）没有骨或筋膜的影响。为了量化这种关系，对新西兰白色兔（质量= 2.5 +/- 0.5 kg，n = 12）的分离TA进行长度-张力实验。将膝关节固定在定制夹具中，将TA的远端肌腱连接到骨水泥上，并将360 μ m光纤压力传感器插入TA中。刺激腓神经以确定最佳长度（L-0）。使用40 Hz等长收缩创建长度-张力曲线，每次收缩之间有2 min休息间隔。测量从L-0- 50% L-f开始，进行到L-0 + 50% L-f，每次收缩后以5% L-f增量改变长度-张力。定性地，等长收缩的长度-张力曲线由主动和被动条件下的长度-压力曲线模仿。对每只动物的长度张力曲线的上升和下降肢体以及主动和被动条件单独进行线性回归。压力-力决定系数的范围为0.138-0.963的主动上升肢体和0.343-0.947的主动下降肢体。上升肢的被动压力决定系数范围为0.045-0.842，下降肢的被动压力决定系数范围为0.672-0.982。这些数据表明，IMP测量提供了相对肌肉力量的相当准确的指数，特别是在肌肉长度长于最佳的情况下。(C)2003爱思唯尔科技有限公司版权所有。
The purpose of this study was to quantify the relationship between intramuscular pressure (IMP) and muscle force during isometric muscle contraction of the rabbit tibialis anterior (TA) absent the effect of either bone or fascia. To quantify this relationship, length-tension experiments were performed on the isolated TA of the New Zealand White rabbit (mass = 2.5 +/- 0.5 kg, n = 12). The knee was fixed in a custom jig, the distal tendon of the TA was attached to a servomotor, and a 360 mum fiber optic pressure transducer was inserted into the TA. The peroneal nerve was stimulated to define optimal length (L-0). The length-tension curve was created using 40 Hz isometric contractions with 2-min rest intervals between each contraction. Measurements began at L-0-50% L-f and progressed to L-0 + 50% L-f, changing the length-tension in 5% L-f increments after each contraction. Qualitatively, the length-tension curve for isometric contractions was mimicked by the length-pressure curve for both active and passive conditions. Linear regression was performed individually for each animal for the ascending and descending limb of the lengthtension curve and for active and passive conditions. Pressure-force coefficients of determination ranged from 0.138-0.963 for the active ascending limb and 0.343-0.947 for the active descending limb. Passive pressure coefficients of determination ranged from 0.045-0.842 for the ascending limb and 0.672-0.982 for the descending limb. These data indicate that IMP measurement provide a fairly accurate index of relative muscle force, especially at muscle lengths longer than optimal. (C) 2003 Elsevier Science Ltd. All rights reserved.