Governing the Silencing State of Chromatin: The Roles of Polycomb Repressive Complex 1 in Arabidopsis
Governing the Silencing State of Chromatin: The Roles of Polycomb Repressive Complex 1 in Arabidopsis
复制标题
控制染色质的沉默状态：多梳抑制复合物 1 在拟南芥中的作用
DOI：
10.1093/pcp/pcw209
复制
发表时间：
2017
影响因子：
4.9
通讯作者：
Xiaoxue Wang
中科院分区：
文献类型：
--
作者：
Xianli Yang;Aizi Tonga;Bowen Yan;Xiaoxue Wang
多梳族蛋白形成多个蛋白复合物，如多梳抑制复合物（PRC）1和PRC 2，其抑制数千个基因的表达。PRC1和PRC2是拟南芥正常发育所必需的。近年来，对PRC1的功能和调控机制的研究取得了重大进展。本文就拟南芥中PRC1的组成、功能、PRC1向靶基因的募集以及PRC1的功能调控等方面的研究进展进行综述。最后对PRC1在植物基因表达和发育中的作用进行了展望。
Polycomb group proteins form multiple protein complexes such as Polycomb Repressive Complex (PRC) 1 and PRC2, which repress the expression of thousands of genes. PRC1 and PRC2 are essential for normal development in Arabidopsis. Recently, significant progress has been made in understanding the functions and regulatory mechanisms of PRC1. In this review, we focus on the discovery of the composition of PRC1, functions of its components, the recruitment of PRC1 to target genes and the control of PRC1 function in Arabidopsis. Perspectives on dissecting the roles of PRC1 in plant gene expression and development are also given.