A Viewpoint on : Synthesis of Programmable Reaction-Diffusion Fronts Using DNA Catalyzers
A Viewpoint on : Synthesis of Programmable Reaction-Diffusion Fronts Using DNA Catalyzers
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观点：使用 DNA 催化剂合成可编程反应扩散前沿
DOI：
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发表时间：
2015
期刊：
影响因子：
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通讯作者：
A. Estevez
中科院分区：
文献类型：
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作者：
Anton S. Zadorin;Y. Rondelez;J. Galas;A. Estevez
化学研究可以大致分为两类：分析--测量现有的物体和现象--和综合--从更简单的部分构建这些物体和现象。通常，合成滞后于分析：在尝试制造分子之前，首先确定分子的分子式（通常是其结构）。然而，随着化学的进步，研究人员越来越多地尝试先合成，设计实现所需现象的化学系统。由法国CNRS的André Estevez-Torres及其同事领导的团队[1]展示了一种实验工具包，可用于溶液中非线性化学效应的合理工程。利用DNA链在狭窄的通道中移动并在酶的作用下反应，作者能够创造出形状和速度可以精细控制的化学波。他们的设置可以被编程，以产生由化学反应性和分子扩散（“反应扩散”系统）的组合控制的系统中的其他非线性现象的广谱。
Research in chemistry can be roughly divided into two categories: analysis—the measurement of existing objects and phenomena—and synthesis—the construction of those objects and phenomena from simpler pieces. Typically, synthesis lags behind analysis: one first determines the formula of a molecule (and often its structure) before attempting to make it. However, as chemistry advances, investigators are increasingly attempting to synthesize first, designing chemical systems that realize desired phenomena. A team led by André Estevez-Torres at CNRS in France and co-workers [1] has demonstrated an experimental toolkit that could be used for the rational engineering of nonlinear chemical effects in solution. Using DNA strands moving in a narrow channel and reacting under the action of enzymes, the authors are able to create chemical waves whose shapes and velocity can be finely controlled. Their setup could be programmed to yield a broad spectrum of other nonlinear phenomena in systems governed by a combination of chemical reactivity and molecular diffusion (“reaction-diffusion” systems).