Incidence and relative survival of chordomas The Standardized Mortality Ratio and the Impact of Chordomas on a Population
Incidence and relative survival of chordomas The Standardized Mortality Ratio and the Impact of Chordomas on a Population
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DOI：
10.1002/cncr.28032
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发表时间：
2013-06-01
期刊：
影响因子：
6.2
通讯作者：
Weber, Damien C.
中科院分区：
文献类型：
--
作者：
Smoll, Nicolas R.;Gautschi, Oliver P.;Weber, Damien C.
背景：脊索瘤是一种罕见的骨肿瘤，起源于胚胎期脊索的残留物。本研究的数据来自美国国家癌症研究所的监测、流行病学和最终结果（SEER）项目（1973-2009），以计算诊断为颅内和颅外脊索瘤的患者的发病率、相对生存率（RS）和标准化死亡率比（SMR），并评估年龄和性别对这种疾病的影响。结果颅内外脊索瘤的总发病率为8.4/1000万。脉络膜炎患者的中位总生存期为7.7年。男性患者的中位生存期为7.7年，女性患者为7.8年。年轻患者（老年
BACKGROUND Chordomas are rare bone tumors arising from remnants of the embryonic notochord. METHODS Data for this study were obtained from the Surveillance, Epidemiology, and End Results (SEER) Program of the National Cancer Institute (1973-2009) to calculate the incidence, relative survival (RS), and standardized mortality ratio (SMR) of patients diagnosed with intracranial and extracranial chordomas and to assess the effects of age and sex on this disease. RESULTS The overall incidence of extracranial and intracranial chordomas was 8.4 per 10 million population. The median overall survival of patients with chordoma patients was 7.7 years. The median survival was 7.7 years for male patients and 7.8 years for female patients. Younger patients (aged