Nanostructured Calcium Phosphates: Preparation and Their Application in Biomedicine
Nanostructured Calcium Phosphates: Preparation and Their Application in Biomedicine
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DOI：
10.5101/nbe.v4i1.p41-49
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发表时间：
2012-03
影响因子：
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通讯作者：
Feng Chen;Ying-Jie Zhu;J. Wu;Peng Huang;D. Cui
中科院分区：
文献类型：
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作者：
Feng Chen;Ying-Jie Zhu;J. Wu;Peng Huang;D. Cui
由于与钙化组织中的无机成分具有相似的化学性质，合成磷酸钙被认为是具有优异生物相容性的理想生物材料。纳米结构磷酸钙材料在自然界硬组织的形成中起着重要作用。据报道，纳米尺寸的磷酸钙材料能够模拟钙化组织组成成分的尺寸。最近，纳米结构磷酸钙材料的合成与应用已成为一个非常热门的领域。已经报道了许多制备纳米结构磷酸钙的方法，并且获得了各种形态，包括纳米颗粒、片状纳米晶体、纳米针、晶须/纤维/丝、介孔、纳米管、纳米片以及具有三维（3 - D）结构的粉末。预计在生物医学领域，如组织工程支架、药物/基因递送系统和多功能系统中，会对纳米结构磷酸钙进行更多的研究。本文对纳米结构磷酸钙的合成与应用进行了综述和讨论。
Due to the similar chemical properties to the inorganic component in calcified tissues, synthetic calcium phosphate has been considered as ideal biomaterials with excellent biocompatibility. Nanostructured calcium phosphate materials play an important role in the formation of hard tissues in nature. It is reported that calcium phosphates materials in nano-size can mimic the dimensions of constituent components of calcified tissues. Recently, the synthesis and application of nanostructured calcium phosphate materials have become a very hot field. Lots of methods have been reported to prepare nanostructured calcium phosphate, and various morphologies including nanoparticles, plate-like nanocrystals, nano-needles, whiskers/fibres/ wires, mesoporous, nanotubes, nano-blades, and powders with three-dimensional (3-D) structures have been obtained. More studies of nanostructured calcium phosphates are expected in biomedical area, such as tissue engineering scaffolds, drug/gene delivery systems and multifunctional systems. In this article, the synthesis and application of nanostructured calcium phosphates are reviewed and discussed.