Prospects for understanding avirulence gene function.
Prospects for understanding avirulence gene function.
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DOI：
10.1016/s1369-5266(00)00082-0
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发表时间：
2000-08
影响因子：
9.5
通讯作者：
F. White;Bing Yang;L. B. Johnson
中科院分区：
文献类型：
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作者：
F. White;Bing Yang;L. B. Johnson
无毒基因最初是由它们对病原体感染寄主植物能力的负面影响来定义的。目前已知许多无毒基因代表参与宿主-病原菌相互作用的毒力因子的子集。对无毒基因的表征表明，它们编码的蛋白质种类繁多，属于几个基因家族。虽然无毒基因产物的生化功能尚不清楚，但研究已经开始揭示蛋白质的无毒和毒力活性之间的特征和有趣的关系。鉴定关键的毒性因子并阐明它们的功能有望为深入了解植物的防御机制，以及控制植物病害的新的和改进的策略提供帮助。
Avirulence genes are originally defined by their negative impact on the ability of a pathogen to infect their host plant. Many avirulence genes are now known to represent a subset of virulence factors involved in the mediation of the host–pathogen interaction. Characterization of avirulence genes has revealed that they encode an amazing assortment of proteins and belong to several gene families. Although the biochemical functions of the avirulence gene products are unknown, studies are beginning to reveal the features and interesting relationships between the avirulence and virulence activities of the proteins. Identification of critical virulence factors and elucidation of their functions promises to provide insight into plant defense mechanisms, and new and improved strategies for the control of plant disease.