Passive transfer of protection against Bacillus anthracis infection in a murine model

Passive transfer of protection against Bacillus anthracis infection in a murine model
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DOI：
10.1016/s0264-410x(01)00197-9
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发表时间：
2001-08-14
期刊：
VACCINE
影响因子：
5.5
通讯作者：
Williamson, ED
Williamson, ED
中科院分区：
医学3区
文献类型：
--
作者：
Beedham, RJ;Turnbull, PCB;Williamson, ED

文献摘要

被引文献

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被动转移的淋巴细胞和血清免疫小鼠使用两种不同的配方含有重组保护性抗原（rPA）已被用来进一步阐明炭疽杆菌感染的保护机制。结果表明，抗体应答可能在抗B的保护中起重要作用。炭疽菌感染，在测试条件下。这些结果为研制一种改进的炭疽疫苗提供了进一步的数据。皇冠版权所有（C）2001由爱思唯尔科学有限公司出版。保留所有权利。
Passive transfer of lymphocytes and sera from mice immunised using two different formulations containing recombinant protective antigen (rPA) have been used to further elucidate the mechanism of protection against Bacillus anthracis infection. The results demonstrated that an antibody response maybe important in protection against B. anthracis infection, under the conditions tested. The results provide further data for the development of an improved anthrax vaccine. Crown Copyright (C) 2001 Published by Elsevier Science Ltd. All rights reserved.