THE IMPACT OF FATIGUE ON PATIENTS WITH MULTIPLE-SCLEROSIS
THE IMPACT OF FATIGUE ON PATIENTS WITH MULTIPLE-SCLEROSIS
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DOI：
10.1017/s0317167100048691
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发表时间：
1994-02-01
影响因子：
3
通讯作者：
MURRAY, TJ
中科院分区：
文献类型：
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作者：
FISK, JD;PONTEFRACT, A;MURRAY, TJ
虽然疲劳被认为是MS的一种症状，但评估这种症状的方法还不够。我们对85名MS患者和20名高血压患者进行了疲劳影响量表。还评估了神经功能缺损、心理健康和一般健康状况。MS患者报告的疲劳影响显著高于高血压患者。大多数MS患者报告疲劳是他们最严重的症状（14%）或最严重的症状之一（55%）。在MS样本中，疾病分类和神经功能缺损与疲劳影响量表评分关系不大。MS样本中心理健康和一般健康状况的最佳预测模型都将疲劳影响量表作为一个重要因素。这项研究表明：1）疲劳是MS中非常普遍和严重的问题，2）疲劳影响不能通过神经功能缺损的临床测量来预测，3）疲劳对MS患者的心理健康和一般健康状况具有显著影响。
Although fatigue is recognized as a symptom of MS, there have been insufficient methods for evaluating this symptom. We administered the Fatigue Impact Scale to 85 MS patients and 20 hypertensive patients. Neurologic impairment, mental health, and general health status were also assessed. MS patients reported significantly higher fatigue impact than hypertensive patients. Most MS patients reported fatigue as either their worst (14%), or one of their worst (55%) symptoms. Disease classification and neurologic impairment had little bearing on Fatigue Impact Scale scores in the MS sample. The best predictive models for mental health and general health status in the MS sample both included the Fatigue Impact Scale as a significant factor. This study demonstrates that: 1) fatigue is a very prevalent and severe problem in MS, 2) fatigue impact cannot be predicted by clinical measures of neurologic impairment, 3) fatigue has a significant effect on the mental health and general health status of MS patients.