The development of the stria vascularis in the human foetus
The development of the stria vascularis in the human foetus
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DOI：
10.1046/j.1365-2273.2000.00340.x
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发表时间：
2000-04-01
影响因子：
2.1
通讯作者：
Wright, A
中科院分区：
文献类型：
--
作者：
Bibas, A;Liang, J;Wright, A
在81例人胎儿颞骨的台阶切片上，观察了人耳蜗血管纹的发育。原基血管纹是耳蜗管外侧壁上皮细胞的隆起。分化的最初迹象出现在第11周，但直到第17-18周才观察到典型的三板层结构。在这个阶段，在边缘层和间叶层中出现类似的带有缺口核的细胞，这表明一些中间细胞可能是上皮细胞起源的。到第21周时，整体外观与成体结构相似。这发生在Corti隧道开放后1周，可能标志着耳蜗功能的开始。
The development of the stria vascularis in the human cochlea was studied in step sections of 81 human foetal temporal bones. The stria vascularis primordium can be identified as a ridge of epithelial cells on the lateral wall of the cochlear duct. The first signs of differentiation appear at the 11th week, but it is not until the 17th-18th week that the typical trilaminar structure is observed. The appearance of similar cells with notched nuclei in both marginal and mesenchymal layers at this stage suggests the possibility that some of the intermediate cells may be of epithelial origin. By the 21st week, the overall appearance resembles that of the adult structure. This occurs 1 week after the opening of the tunnel of Corti, and possibly marks the onset of cochlear function.