Surface-enhanced Raman spectroscopy coupled with dendritic silver nanosubstrate for detection of restricted antibiotics
Surface-enhanced Raman spectroscopy coupled with dendritic silver nanosubstrate for detection of restricted antibiotics
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DOI：
10.1002/jrs.2505
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发表时间：
2010-07-01
影响因子：
2.5
通讯作者：
Kim, Nam-Jung
中科院分区：
文献类型：
--
作者：
He, Lili;Lin, Mengshi;Kim, Nam-Jung
本研究采用表面增强拉曼光谱（SERS）结合树突银纳米底物，对限制性抗生素进行快速检测和表征。通过简单的取代反应制备了树状银纳米底物，并在去离子水中储存数月。采用银纳米底物，在785 nm近红外激发SERS检测标准溶液中3种限制性抗生素（恩诺沙星、环丙沙星和氯霉素）。SERS能够快速准确地识别和表征三种抗生素。银枝晶表现出满意和一致的性能，分析增强因子接近10(4)。抗生素的检出限和定量限可达到20 ppb的水平。银枝晶可以在去离子水中保存长达6个月，SERS性能没有退化的迹象。这些结果表明，利用SERS与银枝晶耦合进行化学污染物的快速检测、分类和量化具有巨大的潜力。版权所有John Wiley & Sons， Ltd. 2009
Surface-enhanced Raman spectroscopy (SERS) coupled with dendritic silver nanosubstrates was used in this study for rapid detection and characterization of restricted antibiotics. Dendritic silver nanosubstrates were prepared through a simple replacement reaction and stored in deionized water for months. SERS methods with near-IR excitation at 785 nm using silver nanosubstrates were evaluated for detection of three restricted antibiotics (i.e. enrofloxacin, ciprofloxacin, and chloramphenicol) prepared in standard solutions. SERS was capable of identifying and characterizing three antibiotics quickly and accurately. Silver dendrites exhibit satisfactory and consistent performance with an analytical enhancement factor of similar to 10(4). The limit of detection and limit of quantification for antibiotics could reach the level of 20 ppb. Silver dendrites can be kept in deionized water for up to 6 months with no signs of degradation in SERS performance. These results demonstrate a great potential of using SERS coupled with silver dendrites for rapid detection, classification, and quantification of chemical contaminants. Copyright (C) 2009 John Wiley & Sons, Ltd.