Effects of Training on the Distribution of Cardiac Output in Patients with Coronary Artery Disease
Effects of Training on the Distribution of Cardiac Output in Patients with Coronary Artery Disease
复制标题
训练对冠心病患者心输出量分布的影响
作者：
J. P. Clausen;J. Trap
在9例冠状动脉疾病患者中，通过测量心输出量和局部血流参数（肝脏和肌肉血流）来评估静息和运动时的心输出量分布。在7例患者中，在持续4至10周的体育训练计划后获得了重复值。训练后，心输出量在中等负荷下减少（13.1%），导致摄氧量和心输出量之间的关系从高运动变为正常。剧烈运动时，训练后心输出量增加5.5%。肌肉血流量也发生了类似的变化，在次最大负荷时减少（14.9%），在最大负荷时增加（8.6%）。相比之下，在训练后的两种工作负荷下，肝血流量的减少不太明显（差异为7.2%）。训练的这些影响可以解释为外周调节的改变，而不意味着心肌表现的原发性改善。他们一致认为，在训练肌肉的局部变化是重要的，以减少心肌压力功引起的身体条件。
In nine patients with coronary artery disease, cardiac output distribution was evaluated at rest and during exercise by measurement of cardiac output and regional blood flow parameters (hepatic and muscle blood flow). In seven patients repeated values were obtained after a physical training program of 4 to 10 weeks' duration. After training, cardiac output was reduced at moderate work loads (13.1%) causing a change of the relation between oxygen uptake and cardiac output from hyperkinetic to normal. During heavy exercise the cardiac output was increased (5.5%) after training. Similar changes were observed in muscle blood flow, which was reduced at submaximal loads (14.9%) and increased at maximal (8.6%). Hepatic blood flow showed in contrast a less pronounced reduction at both work loads after training (difference, 7.2%). These effects of training could be explained as peripheral regulatory alterations without implying primary improvement in myocardial performance. They are consistent with the view that local changes in the trained muscles are important for the reduction in myocardial pressure-work caused by physical conditioning.