Phase behavior of concentrated hydroxypropyl methylcellulose solution in the presence of mono and divalent salt.
Phase behavior of concentrated hydroxypropyl methylcellulose solution in the presence of mono and divalent salt.
复制标题
DOI：
10.1016/j.carbpol.2013.08.081
复制
发表时间：
2014-01
影响因子：
11.2
通讯作者：
Nalinda Almeida;L. Rakesh;J. Zhao
中科院分区：
文献类型：
--
作者：
Nalinda Almeida;L. Rakesh;J. Zhao
羟丙基甲基纤维素（HPMC）的热可逆溶胶-凝胶转变对于许多药物、化妆品和食品应用是关键的。本研究探讨了盐（NaCl和CaCl 2）对浓缩的低分子量HPMC溶液的粘弹性能的影响，发现凝胶化温度作为盐浓度的函数线性下降，与阳离子的价态和阴离子的摩尔浓度无关。热分析结果表明，NaCl和CaCl 2的熔点下降与离子总数均呈线性关系，这与NaCl和CaCl 2对纯水的熔点下降一致，但线性斜率较大.
Thermo reversible sol–gel transitions of hydroxypropylmethylcellulose (HPMC) are critical for many pharmaceutical, cosmetic, and food applications. This study examined the effects of salt (NaCl and CaCl2) on the viscoelastic properties of concentrated low molecular weight HPMC solutions and found that the gelation temperature decreased linearly as a function of salt concentrations, independent of valency of cations and the mole concentration of anions. Thermal analysis showed that the depression of melting temperature can be fitted for both NaCl and CaCl2as a function of the total number of ions by a single linear curve, which was consistent with the melting point depression of pure water by NaCl and CaCl2, but with a higher linear slope.