The correlation between internal and external markers for abdominal tumors: Implications for respiratory gating
The correlation between internal and external markers for abdominal tumors: Implications for respiratory gating
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DOI：
10.1016/j.ijrobp.2004.12.013
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发表时间：
2005-04-01
影响因子：
7
通讯作者：
Chen, GTY
中科院分区：
文献类型：
--
作者：
Gierga, DP;Brewer, J;Chen, GTY
目的：检查外部患者标记物和腹部肿瘤的呼吸运动的相关性。这种类型的数据是很重要的图像引导治疗技术，如呼吸门控，监测外部fixies.Methods和材料的运动：荧光透视会话4例患者的内部，不透射线的肿瘤基准夹进行了分析，通过计算机视觉技术。的内部剪辑和放置在病人的腹部皮肤surfaces.Results的外部标记的运动进行了量化和correlated：在一般情况下，肿瘤和外部标记的运动有很好的相关性。峰-峰头尾肿瘤运动的最大量为2.5 cm。肿瘤运动与外部标记物运动的比值范围为0.85至7.1。对于给定的外部标记位置，肿瘤位置的变化范围为2至9 mm。呼吸周期范围为2.7至4.5秒，肿瘤和外部标记的频率模式相似。虽然肿瘤运动通常与外部基准标记运动相关性很好，对于给定的标记位置，与外部标记运动和肿瘤位置的变化相比，可能发生相对较大的潜在肿瘤运动。治疗边界应在详细了解肿瘤运动的基础上确定，而不是仅依赖于外部标记信息。(c)2005年爱思唯尔公司
Purpose: The correlation of the respiratory motion of external patient markers and abdominal tumors was examined. Data of this type are important for image-guided therapy techniques, such as respiratory gating, that monitor the movement of external fiducials.Methods and Materials: Fluoroscopy sessions for 4 patients with internal, radiopaque tumor fiducial clips were analyzed by computer vision techniques. The motion of the internal clips and the external markers placed on the patient's abdominal skin surface were quantified and correlated.Results: In general, the motion of the tumor and external markers were well correlated. The maximum amount of peak-to-peak craniocaudal tumor motion was 2.5 cm. The ratio of tumor motion to external-marker motion ranged from 0.85 to 7.1. The variation in tumor position for a given external-marker position ranged from 2 to 9 mm. The period of the breathing cycle ranged from 2.7 to 4.5 seconds, and the frequency patterns for both the tumor and the external markers were similar.Conclusions: Although tumor motion generally correlated well with external fiducial marker motion, relatively large underlying tumor motion can occur compared with external-marker motion and variations in the tumor position for a given marker position. Treatment margins should be determined on the basis of a detailed understanding of tumor motion, as opposed to relying only on external-marker information. (c) 2005 Elsevier Inc.